PHR1055

法莫替丁

Pharmaceutical Secondary Standard; Certified Reference Material

• 同義詞: N′-（氨基磺酰基）-3-([2-（二氨基亚甲基氨基）-4-噻唑基]甲硫基)丙脒
• 經驗公式（希爾表示法）: C₈H₁₅N₇O₂S₃
• CAS號碼: 76824-35-6
• 分子量：: 337.45
• MDL號碼: MFCD00079297
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823085
• NACRES: NA.24

屬性

• 生物源: synthetic
• 品質等級: 300
• 等級: certified reference material; pharmaceutical secondary standard
• agency: BP; EP; USP; traceable to BP 653; traceable to Ph. Eur. F0050000; traceable to USP 1269200
• 蒸汽壓力: <0.0000001 kPa ( 25 °C)
• API 家族: famotidine
• CofA: current certificate can be downloaded
• 包裝: pkg of 1 g
• 儲存條件: protect from light (20 mm aluminium crimp seal for unused portion)
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 顏色: white to pale yellow-white
• mp: 325.4-327.2 °F (163—164°C)
• 溶解度: DMF: freely soluble; acetone: practically insoluble; chloroform: practically insoluble; ethanol: practically insoluble; ether: practically insoluble; ethyl acetate: practically insoluble; glacial acetic acid: freely soluble; methanol: slightly soluble; water: very slightly soluble
• 應用: pharmaceutical (small molecule)
• 形式: neat
• 運輸包裝: ambient
• 儲存溫度: 2-8°C
• SMILES 字串: N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1
• InChI: 1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
• InChI 密鑰: XUFQPHANEAPEMJ-UHFFFAOYSA-N
• 基因資訊: human ... HRH2(3274)

描述

一般說明

Famotidine is a histamine H2-receptor antagonist, which promotes the healing of erosive esophagitis, gastric and duodenal ulcers since it inhibits the gastric acid secretion in humans.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Famotidine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using different chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

H₂组胺受体拮抗剂；抗溃疡剂。

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA7133 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable