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重要文件

BP653

法莫替丁

British Pharmacopoeia (BP) Reference Standard

同義詞:

N′-(氨基磺酰基)-3-([2-(二氨基亚甲基氨基)-4-噻唑基]甲硫基)丙脒

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About This Item

經驗公式(希爾表示法):
C8H15N7O2S3
CAS號碼:
分子量::
337.45
MDL號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

agency

BP

API 家族

famotidine

形狀

solid

儲存期限

limited shelf life, expiry date on the label

包裝

pkg of 100 mg

製造商/商標名

BP

儲存條件

OK to freeze

顏色

white

mp

162-165 °C

溶解度

water: insoluble

應用

pharmaceutical
pharmaceutical small molecule

形式

neat

運輸包裝

ambient

儲存溫度

2-8°C

SMILES 字串

N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1

InChI

1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)

InChI 密鑰

XUFQPHANEAPEMJ-UHFFFAOYSA-N

基因資訊

human ... HRH2(3274)

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一般說明

Famotidine is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Famotidine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Famotidine Tablets
  • 生化/生理作用

    H2组胺受体拮抗剂;抗溃疡剂。

    包裝

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    其他說明

    Sales restrictions may apply.

    儲存類別代碼

    11 - Combustible Solids

    水污染物質分類(WGK)

    WGK 2

    閃點(°F)

    Not applicable

    閃點(°C)

    Not applicable


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    分析證明 (COA)

    Lot/Batch Number

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    存取文件庫

    Famotidine
    British Pharmacopeia
    British Pharmacopoeia, 29(1-2), 247-254 (2020)
    Stability indicating method for famotidine in pharmaceuticals using porous graphitic carbon column
    Helali N and Monser L
    Journal of Separation Science, 31(2) (2008)
    Capillary zone electrophoresis method for the determination of famotidine and related impurities in pharmaceuticals
    Helali N, et al.
    Talanta, 74(4) (2008)
    Potentiometric determination of famotidine in pharmaceutical formulations
    Ayad MM, et al.
    Journal of Pharmaceutical and Biomedical Analysis, 29(1-2) (2002)
    Determination of cimetidine, famotidine, and ranitidine hydrochloride in the presence of their sulfoxide derivatives in pure and dosage forms by high-performance thin-layer chromatography and scanning densitometry
    Kelani KM, et al.
    Journal of AOAC (Association of Official Analytical Chemists) International, 85(5), 1015-1020 (2002)

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