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Key Documents

L0420000

左羟丙哌嗪

European Pharmacopoeia (EP) Reference Standard

同義詞:

(2S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol

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About This Item

經驗公式(希爾表示法):
C13H20N2O2
CAS號碼:
分子量::
236.31
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

levodropropizine

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

InChI

1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2/t13-/m0/s1

InChI 密鑰

PTVWPYVOOKLBCG-ZDUSSCGKSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Levodropropizine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Kyung Hee Park et al.
Yonsei medical journal, 54(1), 262-264 (2012-12-12)
We experienced a case of immunoglobulin E (IgE) mediated anaphylaxis to levodropropizine. The patient was an 18-year old Korean woman. After taking the common cold medication including acetaminophen, domperidone, and levodropropizine, skin rash, angioedema and anaphylaxis were developed immediately. As
E Catena et al.
Pulmonary pharmacology & therapeutics, 10(2), 89-96 (1997-01-01)
The results of a double-blind, randomized clinical trial involving 209 adult patients of either sex with moderate non-productive cough are reported. The therapeutic efficacy and the tolerability of levodropropizine syrup (60 mg t.i.d. for 5 days) was evaluated in comparison
S Franova et al.
Bratislavske lekarske listy, 105(5-6), 203-206 (2004-11-13)
Cough is the most important defence reflex of the airways. Little information exists about participation of the ion channels in the mechanism of the cough reflex. The aim of the study was to investigate the effect of diltiazem administration on
F Tagliaro et al.
Journal of chromatography. B, Biomedical applications, 685(1), 165-170 (1996-10-11)
The present paper describes a new high-performance liquid chromatographic method with fluorescence detection for the analysis of levodropropizine [S-(-)-3-(4-phenylpiperazin-1-yl)-propane-1,2-diol] (Levotuss), an anti-tussive drug, in human serum and plasma. A reversed-phase separation of levodropropizine was coupled with detection of the native
R Bossi et al.
Clinical trials and meta-analysis, 29(1), 9-20 (1994-03-09)
The antitussive compound Levodropropizine (LD) is active in animal bronchoconstriction induced by histamine and capsaicin and in man protects from bronchoconstriction induced by capsaicin. The primary objective of this study was to evaluate the mechanism of action of LD given

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