推薦產品
等級
pharmaceutical primary standard
API 家族
ethacrynic acid
製造商／商標名
EDQM
應用
pharmaceutical (small molecule)
形式
neat
儲存溫度
2-8°C
SMILES 字串
ClC1=C(Cl)C(C(C(CC)=C)=O)=CC=C1OCC(O)=O
InChI
1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17)
InChI 密鑰
AVOLMBLBETYQHX-UHFFFAOYSA-N
基因資訊
human ... SLC12A1(6557)
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一般說明
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
應用
Ethacrynic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包裝
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他說明
Sales restrictions may apply.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
[Action and mode of action of a new original diuretic: ethacrynic acid].
M Salvador et al.
Journal de medecine de Bordeaux et du Sud-Ouest, 143(8), 1105-1118 (1966-08-01)
Toxicity of ethacrynic acid and furosemide.
L B Cooperman et al.
American heart journal, 85(6), 831-834 (1973-06-01)
J H Ploemen et al.
Xenobiotica; the fate of foreign compounds in biological systems, 23(8), 913-923 (1993-08-01)
1. The diuretic drug ethacrynic acid (EA) is a potent reversible inhibitor of rat and human glutathione S-transferases (GST), with I50-values (microM) of 4.6-6.0, 0.3-1.9 and 3.3-4.8 for alpha, mu and pi-class, respectively. 2. The reversible inhibition by the glutathione
Ototoxicity of ethacrynic acid (a persistent clinical problem).
L P Rybak
The Journal of laryngology and otology, 102(6), 518-520 (1988-06-01)
[Action and mode of action of a new original diuretic: ethacrynic acid].
M Salvador et al.
Actualites cardiologiques et angeiologiques internationales, 15(2), 101-107 (1966-01-01)
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