938785

Sodium tert-butoxide ChemBeads

• 同義詞: NaOtBu, Sodium 2-methylpropan-2-olate, Sodium t-butoxide, Sodium tert-butanolate, Sodium tert-butylate
• CAS號碼: 865-48-5
• MDL號碼: MFCD00040575
• 分類程式碼代碼: 12352100

屬性

• 形狀: solid ()
• 品質等級: 100
• 成份: loading of base, 14-16 wt. %
• SMILES 字串: [Na+].CC(C)(C)[O-]
• InChI: 1S/C4H9O.Na/c1-4(2,3)5;/h1-3H3;/q-1;+1
• InChI 密鑰: MFRIHAYPQRLWNB-UHFFFAOYSA-N

描述

應用

Sodium tert-butoxide may be used as a safe and effective alternative to sodium hydride for the coupling of hydroxyethyl adenine with diethyl p-toluenesulfonyloxymethanephosphonate to form 9-[2-(diethylphosphonomethoxy)ethyl]adenine (diethyl-PMEA), which is a key intermediate to prepare adefovir dipivoxil.
It can also be used:
- To facilitate the coupling of aryl halides with benzene derivatives in the presence of 10-phenanthroline derivative.
- To activate first-row transition-metal pre-catalysts.
- As a base for the amination of aryl chlorides in the presence of a novel palladacyclic precatalyst.
For general uses, product is also available in powdered form (359270)

特點和優勢

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

安全資訊

• 象形圖: GHS02,GHS05
• 訊號詞: Danger
• 危險聲明: H228,H251,H314
• 防範說明: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1B
• 安全危害: EUH014
• 儲存類別代碼: 4.2 - Pyrophoric and self-heating hazardous materials
• 水污染物質分類（WGK）: WGK 3