939048

Lithium bis(trimethylsilyl)amide ChemBeads

• 同義詞: Hexamethyldisilazane lithium salt ChemBeads
• 經驗公式（希爾表示法）: LiC₆H₁₈NSi₂
• 分子量：: 167.33
• 分類程式碼代碼: 12352100

屬性

• 描述: Organic Salt
• 品質等級: 100
• 形狀: solid
• 成份: 14-16 wt% loading of base
• 反應適用性: core: lithium
• SMILES 字串: [Li]N([Si](C)(C)C)[Si](C)(C)C
• InChI: 1S/C6H18NSi2.Li/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
• InChI 密鑰: YNESATAKKCNGOF-UHFFFAOYSA-N

描述

一般說明

Lithium bis(trimethylsilyl)amide is a non-nucleophilic strong Brønsted base, which is generally soluble in most of the nonpolar organic solvents. It is most commonly employed in organic reactions.

應用

Base employed in generating enolates for the preparation of lactone precursors, pyranones, and cyclohexanes. Used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines.[6] Also used in a novel three-step synthesis of disubstituted 1,2,5-thiadiazoles. For general uses, product is also available in powdered form (324620)

特點和優勢

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

其他說明

• High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads
• Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughout Experimentation
• ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

安全資訊

• 象形圖: GHS02,GHS05
• 訊號詞: Danger
• 危險聲明: H228,H251,H314
• 防範說明: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1B
• 安全危害: EUH014
• 儲存類別代碼: 4.2 - Pyrophoric and self-heating hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 62.6 °F - closed cup
• 閃點（°C）: 17 °C - closed cup