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60634

Sigma-Aldrich

过氧化氢酶 来源于溶壁微球菌

solution, dark brown

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

生物源

bacterial (Micrococcus lysodeikticus)

品質等級

形狀

solution

比活性

65,000-150,000 U/mL

分子量

Mr ~230000

技術

microbe id | metabolite detection: suitable

顏色

dark brown

溶解度

0.05 M phosphate buffer pH 7.0: soluble, clear, brown (1:10)

Protein ID登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

InChI 密鑰

NUVBSKCKDOMJSU-UHFFFAOYSA-N

一般說明

研究领域:细胞信号传导

过氧化氢酶(CAT)是一种抗氧化酶,由CAT基因家族编码。该酶在大多数好氧生物中普遍存在。

應用

裂解溶壁微球菌的过氧化氢酶已被用于通过体外生物催化级联消除糖类似物合成过程中过量的过氧化氢产生。它也被用作通过间接测量催化活性来评估氧化应激的标准。

生化/生理作用

过氧化氢酶能迅速将过氧化氢转化为氧气和水。它表现出抗氧化活性,并引发对活性氧(ROS)的防御机制。过氧化氢酶在自然界以及纺织、制药和乳制品等各种行业中起着中和有害过氧化氢的作用。微小球菌赖氨酸过氧化氢酶是一种含血红素的蛋白质。过氧化氢酶与参与过氧化氢(H2O2)处理的多种关键细胞系统一起,在调节细胞氧化还原平衡和辅助细胞和细胞间信号传递方面起着关键作用。

單位定義

1U对应于在pH7.0和25℃下,每分钟分解1 μmol H2O2 所需的酶量

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Resp. Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves


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Hessam Sepasi Tehrani et al.
Progress in biophysics and molecular biology, 140, 5-12 (2018-03-14)
Catalase is one of the firsts in every realm of biological sciences. At the same time it also has a number of unusual features. It has one of the highest turnover numbers of all enzymes. It is essential for neutralizing
Pablo Burraco et al.
BMC evolutionary biology, 17(1), 164-164 (2017-07-08)
Adaptive plasticity is essential for many species to cope with environmental heterogeneity. In particular, developmental plasticity allows organisms with complex life cycles to adaptively adjust the timing of ontogenetic switch points. Size at and time to metamorphosis are reliable fitness
Ivan Gomez-Mestre et al.
PloS one, 8(12), e84266-e84266 (2013-12-21)
Many amphibian species exploit temporary or even ephemeral aquatic habitats for reproduction by maximising larval growth under benign conditions but accelerating development to rapidly undergo metamorphosis when at risk of desiccation from pond drying. Here we determine mechanisms enabling developmental
Margarita Florencio et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 242, 110654-110654 (2020-01-12)
Organisms are exposed to multiple environmental factors simultaneously to which they often respond behaviorally, morphologically and/or physiologically. Amphibian larvae are quite plastic and efficiently adjust their phenotype and physiology to the reigning local conditions. Here we tested whether the combination
An improved procedure using ferricyanide for detecting catalase isozymes.
W Woodbury et al.
Analytical biochemistry, 44(1), 301-305 (1971-11-01)

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