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Merck
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重要文件

32472

Supelco

Cefquinome sulfate

VETRANAL®, analytical standard

同義詞:

(6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(5,6,7,8-tetrahydroquinolin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate sulfate, Cefquinome sulphate

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About This Item

經驗公式(希爾表示法):
C23H24N6O5S2 · H2SO4
CAS號碼:
分子量::
626.68
Beilstein:
11333438
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

產品線

VETRANAL®

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

SMILES 字串

OS([O-])(=O)=O.CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(C[n+]3cccc4CCCCc34)=C(N2C1=O)C(O)=O)c5csc(N)n5

InChI

1S/C23H24N6O5S2.H2O4S/c1-34-27-16(14-11-36-23(24)25-14)19(30)26-17-20(31)29-18(22(32)33)13(10-35-21(17)29)9-28-8-4-6-12-5-2-3-7-15(12)28;1-5(2,3)4/h4,6,8,11,17,21H,2-3,5,7,9-10H2,1H3,(H3-,24,25,26,30,32,33);(H2,1,2,3,4)/b27-16-;/t17-,21-;/m1./s1

InChI 密鑰

KYOHRXSGUROPGY-OFNLCGNNSA-N

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一般說明

Cefquinome sulfates are veterinary, parenteral, fourth-generation cephalosporins belonging to the aminothiazolyl class of compounds. They exhibit broad-spectrum antimicrobial activity against gram-positive and gram-negative bacteria such as Pseudomonas aeruginosa and Enterobacteriaceae.

應用

Cefquinome sulfate may be used as an analytical reference standard for the determination of the analyte in:
  • Pharmaceutical dosage form by reversed phase high performance liquid chromatography (RP-HPLC).


It may be used as a precursor for the preparation of cefquinome that can be employed as an analytical reference standard for the analysis of the analyte in:
  • Bovine milk as well as muscle and kidney samples by HPLC and LC coupled to tandem mass spectrometry (MS/MS), respectively.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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分析證明 (COA)

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存取文件庫

Residue analysis of 15 penicillins and cephalosporins in bovine muscle, kidney and milk by liquid chromatography-tandem mass spectrometry.
Becker M, et al.
Analytica Chimica Acta, 520(1-2), 19-32 (2004)
Dongbo Li et al.
Colloids and surfaces. B, Biointerfaces, 182, 110323-110323 (2019-07-20)
Staphylococcus aureus (S. aureus) has the propensity to form biofilms, which eventually cause antibiotic resistance and treatment failure. Cefquinome sulfate (CS) is an animal-specific antibacterial agent for S. aureus infection. In this work, CS cationic proliposomes (CSCPs) were prepared by
Determination of cephalosporins in raw bovine milk by high-performance liquid chromatography.
S?rensen LK and Snor LK
Journal of Chromatography A, 882(1-2), 145-151 (2000)
Aleksandar Siljanoski et al.
The Journal of dairy research, 85(3), 321-326 (2018-07-04)
The purpose of this study was to determine tetracycline and other antimicrobial residues in milk from dairy cows treated for clinical mastitis. Data on cow health and drugs used were obtained from the farm veterinarians. A milk sample from each
Ivana G Castilho et al.
Journal of dairy science, 100(8), 6414-6421 (2017-06-03)
Staphylococcus aureus is a common pathogen that causes subclinical bovine mastitis due to several virulence factors. In this study, we analyzed S. aureus isolates collected from the milk of cows with subclinical mastitis that had 8 possible combinations of bap

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