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Key Documents

26210

Sigma-Aldrich

3-氯丙酰氯

purum, ≥98.0% (GC)

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About This Item

線性公式:
ClCH2CH2COCl
CAS號碼:
分子量::
126.97
Beilstein:
635814
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

等級

purum

化驗

≥98.0% (GC)

折射率

n20/D 1.457 (lit.)
n20/D 1.457

bp

143-145 °C (lit.)

密度

1.324 g/mL at 20 °C
1.33 g/mL at 25 °C (lit.)

SMILES 字串

ClCCC(Cl)=O

InChI

1S/C3H4Cl2O/c4-2-1-3(5)6/h1-2H2

InChI 密鑰

INUNLMUAPJVRME-UHFFFAOYSA-N

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應用

3-氯丙酰氯已用于:
  • 微波促进的3,5-二取代2-硫代四氢嘧啶-4-酮的液相合成
  • 制备异硫氰酸酯基改性的亲水性和大孔聚合物树脂
  • 合成潜在抗癌药二乙氨基丙酰胺基-羟基蒽醌

象形圖

Skull and crossbonesCorrosion

訊號詞

Danger

危險分類

Acute Tox. 1 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A

安全危害

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 1

閃點(°F)

158.9 °F - closed cup

閃點(°C)

70.5 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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Wen-Ben Yeh et al.
Molecular diversity, 7(2-4), 185-198 (2004-02-12)
An efficient, microwave-assisted method for the liquid-phase combinatorial synthesis of 3,5-disubstituted thiohydantoins and 3,5-disubstituted 2-thioxotetrahydropyrimidin-4-ones has been developed. In synthesizing thiohydantoins, Fmoc-protected amino acids were coupled with polymer support and then deprotected to give primary amines. While in synthesizing thioxotetrahydropyrimidinones
M Hasegawa et al.
Biotechnology and bioengineering, 36(3), 219-223 (1990-07-01)
Hydrophilic and macroporous polymer resins composed of glycerylmethacrylate, styrene, and divinylbenzene were quite easily modified with isothiocyanate groups using a Friedel-Crafts reaction with 3-chloropropionyl chloride and subsequent nucleophilic reaction with KSCN. Alkaline phosphatase and trypsin could be covalently bound to
C Antonello et al.
Archiv der Pharmazie, 322(9), 541-544 (1989-09-01)
A number of new 9,10-anthracenediones were obtained, bearing one or two hydroxyl groups and one positively charged side chain at different positions of the aromatic ring system (compounds 1-5 in Chart 1). These derivatives resemble the anticancer agents mitoxantrone and

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