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Merck
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Key Documents

147443

Sigma-Aldrich

3-氯丙酰氯

technical grade

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About This Item

線性公式:
ClCH2CH2COCl
CAS號碼:
分子量::
126.97
Beilstein:
635814
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

等級

technical grade

品質等級

形狀

liquid

折射率

n20/D 1.457 (lit.)

bp

143-145 °C (lit.)

密度

1.33 g/mL at 25 °C (lit.)

官能基

acyl chloride
chloro

SMILES 字串

ClCCC(Cl)=O

InChI

1S/C3H4Cl2O/c4-2-1-3(5)6/h1-2H2

InChI 密鑰

INUNLMUAPJVRME-UHFFFAOYSA-N

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應用

3-Chloropropionyl chloride was used to modify hydrophilic and macroporous polymer resins composed of glycerylmethacrylate, styrene and divinylbenzene. It was used in the synthesis of diethylaminopropionamido-hydroxy-anthraquinones, which are potential anticancer agents.

象形圖

Skull and crossbonesCorrosion

訊號詞

Danger

危險分類

Acute Tox. 1 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A

安全危害

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 1

閃點(°F)

158.9 °F - closed cup

閃點(°C)

70.5 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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M Hasegawa et al.
Biotechnology and bioengineering, 36(3), 219-223 (1990-07-01)
Hydrophilic and macroporous polymer resins composed of glycerylmethacrylate, styrene, and divinylbenzene were quite easily modified with isothiocyanate groups using a Friedel-Crafts reaction with 3-chloropropionyl chloride and subsequent nucleophilic reaction with KSCN. Alkaline phosphatase and trypsin could be covalently bound to
C Antonello et al.
Archiv der Pharmazie, 322(9), 541-544 (1989-09-01)
A number of new 9,10-anthracenediones were obtained, bearing one or two hydroxyl groups and one positively charged side chain at different positions of the aromatic ring system (compounds 1-5 in Chart 1). These derivatives resemble the anticancer agents mitoxantrone and

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