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等級
analytical standard
品質等級
化驗
≥99.0% (HPLC)
儲存期限
limited shelf life, expiry date on the label
技術
HPLC: suitable
gas chromatography (GC): suitable
應用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
儲存溫度
−20°C
SMILES 字串
O=C1N(CCCCC(O)C)C(N(C)C2=C1N(C)C=N2)=O
InChI
1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3
InChI 密鑰
NSMXQKNUPPXBRG-UHFFFAOYSA-N
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一般說明
Lisofylline (LSF) is a synthetically modified methylxanthine which is known to exhibit various therapeutic properties. It is a potent anti-inflammatory agent and an antioxidant with the ability to suppress oxygen radical production. LSF is used for treating acute lung injury and also has a role in the early treatment of diabetes.
應用
Lisofylline may be used as an analytical reference standard for the determination of the analyte in rat plasma by various high-performance liquid chromatography (HPLC) based techniques.
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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Lisofylline, a novel antiinflammatory agent, protects pancreatic $\beta$-cells from proinflammatory cytokine damage by promoting mitochondrial metabolism
Endocrinology, 143(6), 2341-2348 (2002)
Combined treatment with lisofylline and exendin-4 reverses autoimmune diabetes
Biochemical and Biophysical Research Communications, 344(3), 1017-1022 (2006)
Lisofylline: a potential lead for the treatment of diabetes
Biochemical Pharmacology, 69(1), 1-5 (2005)
Simultaneous estimation of lisofylline and pentoxifylline in rat plasma by high performance liquid chromatography-photodiode array detector and its application to pharmacokinetics in rat
Journal of Chromatography. B, Biomedical Sciences and Applications, 1061(1), 49-56 (2017)
Validation of a high
Acta Poloniae Pharmaceutica, 66(3), 215-224 (2009)
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