推薦產品
生物源
rabbit
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
liquid
不包含
preservative
物種活性
human, mouse, rat
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
avoid repeated freeze/thaw cycles
同型
IgG
運輸包裝
wet ice
儲存溫度
−70°C
目標翻譯後修改
unmodified
基因資訊
human ... PPARGC1A(10891)
一般說明
Protein G purified rabbit polyclonal antibody. Recognizes the ~113 kDa PGC-1α protein.
Recognizes the ~113 kDa PGC-1α protein in BAT cells.
This Anti-PGC-1α Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation for the detection of PGC-1α.
免疫原
A recombinant protein consisting of amino acids 1-120 of mouse PGC-1α
應用
Immunoblotting (not recommended)
Immunoprecipitation (1-2 g/100-200 g total protein)
警告
Toxicity: Regulatory Review (Z)
外觀
In 50 mM PBS
分析報告
Positive Control
Brown adipose tissue from mice exposed to cold
Brown adipose tissue from mice exposed to cold
其他說明
Chang, J.S., et al. 2010. J. Biol. Chem. 285, 18039.
Zhang, Y., et al. 2009. J. Biol. Chem. 284, 32813.
Lai, L., et al. 2008. Genes Dev. 14, 1948.
Rodgers, J.T., et al. 2008. FEBS Lett. 582, 46.
Mazzucotelli, A., et al. 2007. Diabetes 10, 2467.
Nemoto, S., et al. 2005. J. Biol. Chem. 16, 16456.
Zhang, Y., et al. 2009. J. Biol. Chem. 284, 32813.
Lai, L., et al. 2008. Genes Dev. 14, 1948.
Rodgers, J.T., et al. 2008. FEBS Lett. 582, 46.
Mazzucotelli, A., et al. 2007. Diabetes 10, 2467.
Nemoto, S., et al. 2005. J. Biol. Chem. 16, 16456.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Santosh Bhat et al.
Circulation. Heart failure, 12(3), e005529-e005529 (2019-02-26)
Proper dynamics of RNA polymerase II, such as promoter recruitment and elongation, are essential for transcription. PGC-1α (peroxisome proliferator-activated receptor [PPAR]-γ coactivator-1α), also termed PPARGC1a, is a transcriptional coactivator that stimulates energy metabolism, and PGC-1α target genes are downregulated in
Kennedy C Whitley et al.
Physiological reports, 8(14), e14517-e14517 (2020-07-31)
Calcineurin is a Ca2+ -dependent serine/threonine phosphatase that dephosphorylates nuclear factor of activated T cells (NFAT), allowing for NFAT entry into the nucleus. In skeletal muscle, calcineurin signaling and NFAT activation increases the expression of proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α)
Valerio Donato et al.
Nature cell biology, 19(4), 341-351 (2017-03-21)
Self-renewing naive mouse embryonic stem cells (mESCs) contain few mitochondria, which increase in number and volume at the onset of differentiation. KBP (encoded by Kif1bp) is an interactor of the mitochondrial-associated kinesin Kif1Bα. We found that TDH, responsible for mitochondrial
Susana Peralta et al.
Journal of cell science, 131(13) (2018-06-15)
Mutations in the mitochondrial inner membrane ATPase ATAD3A result in neurological syndromes in humans. In mice, the ubiquitous disruption of Atad3 (also known as Atad3a) was embryonic lethal, but a skeletal muscle-specific conditional knockout (KO) was viable. At birth, ATAD3
Juli Bai et al.
Communications biology, 3(1), 257-257 (2020-05-24)
Obesity is a global epidemic that is caused by excessive energy intake or inefficient energy expenditure. Brown or beige fat dissipates energy as heat through non-shivering thermogenesis by their high density of mitochondria. However, how the mitochondrial stress-induced signal is
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