SCT091

BioTracker NIR-HO Live Cell Dye

• 同義詞: BioTracker NIR-HO Live Cell Dye
• 分類程式碼代碼: 12352207
• NACRES: NA.47

屬性

• 形狀: lyophilized
• 分子量: calculated mol wt 506.6
• 包裝: pkg of 1 mg
• 製造商／商標名: Millipore
• 儲存條件: protect from light
• 增長模式: N/A
• 運輸包裝: ambient
• 儲存溫度: −20°C

描述

一般說明

Mercury (Hg) is considered an extremely toxic heavy metal which is extremely harmful to human health. Researchers are investigating the role of Hg2+-induced oxidative stress, via peroxynitrite (ONOO−) level upregulation, in the pathogenic mechanisms of mercury toxicity. BioTracker NIR-HO Live Cell Dye is a near-infrared (NIR) fluorescent probe for the detection and visualization of Hg2+-induced ONOO− generation in vitro and in vivo. This fluorescent probe was designed with a “dual-key-and-lock” strategy where emission can only be switched on in the presence of both Hg2+ and ONOO− (1). It provides an effective method for detecting and imaging Hg2+ and ONOO- in oxidative stress studies and in the development of detoxifying drugs. Spectral PropertiesExcitation: 550 nmEmission: 680 nmReference:1. Yang, Xiaopeng, et al. "Imaging Hg2+-induced oxidative stress by NIR molecular probe with “dual-key-and-lock” strategy." Analytical Chemistry 92.17 (2020): 12002-12009.

應用

Purity ≥ 98% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.

特點和優勢

Near-Infrared probe for imaging Hg2+-and ONOO− in mercury-induced oxidative stress studies.

外觀

Lyophilized. Yellow solid.

儲存和穩定性

Store at -20°C, desiccate and protect from light.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable