SCT093

BioTracker Mito-Chloride Live Cell Dye

• 同義詞: BioTracker Mito-Chloride Live Cell Dye
• 分類程式碼代碼: 12352207
• NACRES: NA.47

屬性

• 形狀: lyophilized
• 分子量: calculated mol wt 498.41
• 包裝: pkg of 1 mg
• 製造商／商標名: Millipore
• 儲存條件: protect from light
• 增長模式: N/A
• 運輸包裝: ambient
• 儲存溫度: −20°C

描述

一般說明

Mitochondrial membranes contain several ion channels. Among them, mitochondrial chloride channels are involved in the regulation of the mitochondrial volume, maintenance of the mitochondria membrane potential, and apoptosis. The chloride transport activity of these channels is known to be dependent on the mitochondrial pH, with their activity increasing under acidic conditions and decreasing at pH greater than 7.0 (1). BioTracker Mito-Chloride Live Cell Dye is a mitochondrial Cl- selective fluorescent probe. Fluorescence of probe is insensitive to pH over the physiological pH range and is quenched by Cl- with Stern−Volmer quenching constant of 201 M−1 at pH 7.0 (1). This probe can be used to monitor the effects of substances on chloride levels in mitochondria.Reference:1. Park, Sang-Hyun, et al. "Mitochondrial Cl–-Selective Fluorescent Probe for Biological Applications." Analytical Chemistry 92.18 (2020): 12116-12119.

應用

Purity ≥ 98% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.

特點和優勢

Fluorescent probe for monitoring Cl- in mitochondria.

外觀

Lyophilized. Yellow solid.

儲存和穩定性

Store at -20°C, desiccate and protect from light.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable