SCT086

BioTracker MitoBlue Live Cell Dye

• 分類程式碼代碼: 12352207
• NACRES: NA.47

屬性

• 生物源: Unknown
• 包裝: vial of 1 mg
• 製造商／商標名: Millipore
• 增長模式: N/A
• 技術: cell culture | mammalian: suitable
• 運輸包裝: dry ice
• 儲存溫度: −20°C

描述

一般說明

BioTracker MitoBlue Live Cell Dye is a synthetic bisbenzamidine derivative that selectively stains functional mitochondria while displaying low toxicity, bright blue emission, and high resistance to photobleaching in both live and fixed cells (1). It is a unique mitochondrial dye in that after initially staining mitochondria, the dye is transported to lysosomes in a time-dependent manner. This distinct staining pattern allows for monitoring and tracking the mitochondrial recycling mechanism in living cells (2). MitoBlue has been shown to be suitable for two-photon microscopy using a 740 nm two-photon excitation (TPE) wavelength and emission channel at 480 nm (2).

Spectral Properties</bold>
Absorbance: 329nm
Emission: 420nm

Reference:
1. Sa?nchez, Mateo I., et al. "MitoBlue: a nontoxic and photostable blue-emitting dye that selectively labels functional mitochondria." ACS chemical biology 9.12 (2014): 2742-2747.
2. Sánchez, Mateo I., et al. "MitoBlue as a tool to analyze the mitochondria-lysosome communication." Scientific reports 10.1 (2020): 1-12.

應用

Purity >97% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.

特點和優勢

Live cell imaging dye that stains functional mitochondria and tracks the mitochondrial degradation process and transport to lysosomes.

外觀

Lyophilized. Yellow solid.

儲存和穩定性

Store at -20°C, desiccate and protect from light.Note: Centrifuge vial briefly to collect contents at bottom of vial before opening

其他說明

This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319
• 防範說明: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable