MABT25

Anti-Myosin 2 Antibody, clone 5B11.1

clone 5B11.1, from mouse

• 同義詞: Myosin-2, Myosin heavy chain 2, Myosin heavy chain 2a, MyHC-2a, Myosin heavy chain Iia, MyHC-Iia, Myosin heavy chain, skeletal muscle, adult 2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 5B11.1, monoclonal
• 物種活性: mouse, human, rat
• 技術: immunohistochemistry: suitable; western blot: suitable
• 同型: IgG3κ
• NCBI登錄號: NP_060004
• UniProt登錄號: Q9UKX2
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MYH2(4620)

描述

一般說明

Myosin is a hexameric protein consisting of two heavy chains including Myosin-2 (MYH2), two regulatory light chains, and two alkali light chains. The myosin-2 heavy chain interacts with the actin cytoskeleton and mediates muscle contractility in eukaryotic cells. Defects in myosin-2 result in inclusion body myopathy type 3.

免疫原

KLH-conjugated linear peptide corresponding to mouse Myosin 2.

應用

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

This Anti-Myosin 2 Antibody, clone 5B11.1 is validated for use in Western Blotting, IHC for the detection of Myosin 2.

Western Blot Analysis: 0.5 µg/mL from a representative lot detected Myosin-2 in L6 cell lysate (Myosin may be observed as a smear in some cell lysates).

Western Blot Analysis: A representative lot detected Myosin-2 in mouse heart cell cytosolic extracts.

品質

Evaluated by Immunohistochemistry in human cardiac muscle tissue.

Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Myosin-2 in human cardiac muscle tissue.

標靶描述

~220 kDa observed

外觀

Format: Purified

Purified mouse monoclonal IgG3κ in buffer containing PBS with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Human cardiac muscle tissue

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable