MABS453

Anti-Axin2, clone cond4-1D5 Antibody

clone cond4-1D5, from rat

• 同義詞: Axin-2, Axin-like protein, Axil, Conductin
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rat
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: cond4-1D5, monoclonal
• 物種活性: human
• 技術: immunocytochemistry: suitable; western blot: suitable
• 同型: IgG2aκ
• NCBI登錄號: NP_004646
• UniProt登錄號: Q9Y2T1
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... AXIN2(8313)

描述

一般說明

Axin-2, or Axis inhibition protein 2, is an inhibitor of the Wnt signaling pathway that down-regulates beta-catenin and APC through phosphorylation. Axin-2 abnormalities are linked to defective mismatch repair and have been found to be involved in colorectal cancer (CRC) and oligodontia-colorectal cancer syndrome (ODCRCS). Axin-2 can be found in brain and lymphoblast tissues.

特異性

This monoclonal antibody recognizes both endogeneous and overexpressed Axin2 and does not cross-react with Axin1

免疫原

Linear peptide corresponding to Human Axin 2.

應用

Immunocytochemistry Analysis: 20 μg/mL of this antibody from a representative lot detected Axin2 in HeLa, HEK293 and NIH-3T3 cells.
Western Blotting Analysis: A representative lot of this antibody detected Axin2 in SW 480 cell lines

Research Category
Signaling

Apoptosis & Cancer

Research Sub Category
General Post-translation Modification

This Anti-Axin2, clone cond4-1D5 Antibody is validated for use in Western Blotting and Immunocytochemistry for the detection of Axin2.

品質

Evaluated by Western Blotting in HCT116 cell lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected Axin2 in 10 µg of HCT116 cell lysate.

標靶描述

~ 95 kDa observed

外觀

Protein G Purified

Format: Purified

Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to lot specific datasheet.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable