MABD90

Anti-HLA-DRB1 Antibody, clone DJ9

clone DJ9, from mouse

• 同義詞: Major histocompatibility complex, class II, DRB1, DRB1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: DJ9, monoclonal
• 物種活性: human
• 技術: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• NCBI登錄號: NP_002112
• UniProt登錄號: P01911
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... HLA-DRB1(3123)

描述

一般說明

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. HLA-DRB1 binds peptides derived from antigens that access the endocytic route of antigen presenting cells and presents them on the cell surface for recognition by the CD4 T-cells. Class II molecules are expressed in antigen presenting cells B lymphocytes, dendritic cells, macrophages. HLA-Drb1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. HLA-DRB1, clone DJ9, has been shown to be a relevant marker of bone marrow derived mesenchymal stem cells and their osteogenic derivatives (Andersen, D., et al., 2011).

The previously assigned protein identifier Q5Y7A7 has been merged into P01911. Full details can be found on the UniProt database.

特異性

This antibody recognizes human HLA-DRB1.

免疫原

Whole hMSC-TERT Cells

應用

Detect HLA-DRB1 using this Anti-HLA-DRB1 Antibody, clone DJ9 validated for use in Western Blotting, ICC, IHC, Flow Cytometry.

Research Category
Inflammation & Immunology

Stem Cell Research

Research Sub Category
Immunological Signaling

Mesenchymal Stem Cells

This antibody has been shown to work in Immunocytochemistry (Andersen, D., et al. (2011)). This antibody has been shown to work in Immunohistochemistry (Andersen, D., et al. (2011)). This antibody has been shown to work in Flow Cytometry (Andersen, D., et al. (2011)).

品質

Evaluated by Western Blot in Daudi cell lysates. Western Blot Analysis: A 1:100,000 dilution of this antibody detected HLA-DRB1 in Duadi cell lysates.

標靶描述

~30 kDa observed

外觀

Format: Purified

分析報告

Control
Daudi cell lysates

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable