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Merck
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Key Documents

MABD24A4

Sigma-Aldrich

Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor™ 488 conjugate

clone 7F7.1, from mouse, ALEXA FLUOR™ 488

同義詞:

Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

100

共軛

ALEXA FLUOR™ 488

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

7F7.1, monoclonal

物種活性

human

技術

immunocytochemistry: suitable

同型

IgG2a

NCBI登錄號

NP_079141

UniProt登錄號

Q9H9S0

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... NANOG(79923)

一般說明

NANOG (Homeobox protein NANOG) is a member of the Nanog homeobox family of DNA-binding proteins. It is expressed in embryonic stem cells and confers pluripotency on these cells. Once embryonic stem cells become differentiated, NANOG expression is suppressed. NANOG is involved in the Hedgehog/Gli1 signaling pathway which has been implicated in the development and growth of various types of tumors. NANOG has also been identified as a key transcription factor used to generate induced pluripotent stem cells.

應用

Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor 488 conjugate.

品質

Evaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected NANOG in H9 human embryonic stem cells.

標靶描述

The uncojugated parent antibody (Catalog No. MABD24) has an observed MW of 39 kDa

外觀

Purified mouse monoclonal IgG2a conjugated to Alexa Fluor™ 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Breanna S Borys et al.
Stem cell research & therapy, 12(1), 55-55 (2021-01-14)
Human induced pluripotent stem cells (hiPSCs) hold enormous promise in accelerating breakthroughs in understanding human development, drug screening, disease modeling, and cell and gene therapies. Their potential, however, has been bottlenecked in a mostly laboratory setting due to bioprocess challenges
Quan Qi et al.
International journal of molecular medicine, 35(3), 569-578 (2014-12-20)
The present study aimed to investigate the X chromosome inactivation (XCI) status in long-term cultured human parthenogenetic embryonic stem cells. One human embryonic stem (hES) cell line and 2 human parthenogenetic embryonic stem (hPES) cell lines were subjected to long-term
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Vanessa Sauer et al.
Cell transplantation, 25(12), 2221-2243 (2016-08-12)
Although several types of somatic cells have been reprogrammed into induced pluripotent stem cells (iPSCs) and then differentiated to hepatocyte-like cells (iHeps), the method for generating such cells from renal tubular epithelial cells shed in human urine and transplanting them
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