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Merck
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重要文件

MAB5618

Sigma-Aldrich

Anti-Serotonin Transporter Antibody

ascites fluid, Chemicon®

同義詞:

SERT

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

ascites fluid

抗體產品種類

primary antibodies

無性繁殖

monoclonal

物種活性

primate, human

應無反應活性

rat

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

特異性

Serotonin Transporter, human and non-human primate.

免疫原

Synthetic peptide from human serotonin transporter.

應用

Anti-Serotonin Transporter Antibody detects level of Serotonin Transporter & has been published & validated for use in IH.
Immunohistochemistry: 1:500-1:1,000 on 10% formalin fixed, paraffin embedded tissue from human Medulla oblongata. Suggested antigen retrieval method is Heat Induced Epitope Retrieval (HIER): Citrate Buffer pH 6.0.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

外觀

Ascites

儲存和穩定性

Maintain at -20degC in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Serotonin neurons derived from rhesus monkey embryonic stem cells: similarities to CNS serotonin neurons
Salli, Ugur, et al
Experimental neurology, 188, 351-364 (2004)
Anke J Borgers et al.
Frontiers in neuroscience, 8, 106-106 (2014-05-27)
That serotonin plays a role in the regulation of feeding behavior and energy metabolism has been known for a long time. Serotonin transporters (SERT) play a crucial role in serotonin signaling by regulating its availability in the synaptic cleft. The
Smriti Patodia et al.
Brain pathology (Zurich, Switzerland), 32(5), e13074-e13074 (2022-04-29)
Several lines of evidence link deficient serotonin function and SUDEP. Chronic treatment with serotonin reuptake inhibitors (SRIs) reduces ictal central apnoea, a risk factor for SUDEP. Reduced medullary serotonergic neurones, modulators of respiration in response to hypercapnia, were reported in
C H Lew et al.
Molecular autism, 11(1), 12-12 (2020-02-07)
Williams syndrome (WS) and autism spectrum disorder (ASD) are neurodevelopmental disorders that demonstrate overlapping genetic associations, dichotomous sociobehavioral phenotypes, and dichotomous pathological differences in neuronal distribution in key social brain areas, including the prefrontal cortex and the amygdala. The serotonergic
A L Bauman et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 20(20), 7571-7578 (2000-10-12)
Presynaptic transporter proteins regulate the clearance of extracellular biogenic amines after release and are important targets for multiple psychoactive agents, including amphetamines, cocaine, and antidepressant drugs. Recent studies reveal that dopamine (DA), norepinephrine (NE), and serotonin (5-HT) transporters (DAT, NET

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