推薦產品
生物源
mouse
品質等級
抗體表格
ascites fluid
無性繁殖
1G9.39A5, monoclonal
物種活性
human, mouse, rat, rabbit
製造商／商標名
Chemicon®
技術
western blot: suitable
同型
IgG2b
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... GRIN2D(2906)
特異性
NMDAR2D，C末端。通过蛋白质印迹法，抗体与约145的弱条带反应。根据所用样品和抗体浓度，可观察到约75 kDa的额外条带。
免疫原
来自大鼠NMDAR2D的重组蛋白。
應用
抗NMDAR2D抗体检测NMDAR2D水平，&已发布&验证可用于WB。
研究子类别
神经递质&受体
神经递质&受体
研究类别
神经科学
神经科学
蛋白质印迹：针对大鼠脑裂解物为1:500-1:1,000。
最佳工作稀释度必须由最终使用者进行确定。
最佳工作稀释度必须由最终使用者进行确定。
外觀
液体。
儲存和穩定性
接收后，以未稀释的等分试样在-20°C下保存长达6个月。应避免反复冻/融循环。
分析報告
对照
大鼠前脑或小脑。
大鼠前脑或小脑。
其他說明
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Sharon A Swanger et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(48), 15971-15983 (2015-12-04)
The GluN2D subunit of the NMDA receptor is prominently expressed in the basal ganglia and associated brainstem nuclei, including the subthalamic nucleus (STN), globus pallidus, striatum, and substantia nigra. However, little is known about how GluN2D-containing NMDA receptors contribute to
Gajanan P Shelkar et al.
Scientific reports, 9(1), 7572-7572 (2019-05-22)
The GluN2C- and GluN2D-containing NMDA receptors are distinct from GluN2A- and GluN2B-containing receptors in many aspects including lower sensitivity to Mg2+ block and lack of desensitization. Recent studies have highlighted the unique contribution of GluN2C and GluN2D subunits in various
D J Laurie et al.
Brain research. Molecular brain research, 51(1-2), 23-32 (1998-01-14)
Mouse monoclonal antibodies were raised against bacterially expressed protein sequences of the NR2A, NR2B, NR2C and NR2D subunits of the rat NMDA receptor. From immunoblots of rat brain proteins, the apparent molecular weights of these subunits were 165, 170, 135
Jinxu Liu et al.
Neurobiology of disease, 150, 105254-105254 (2021-01-10)
Globus pallidus externa (GPe) is a nucleus in the basal ganglia circuitry involved in the control of movement. Recent studies have demonstrated a critical role of GPe cell types in Parkinsonism. Specifically increasing the function of parvalbumin (PV) neurons in
Jeremy S Lum et al.
Neurochemical research, 43(8), 1683-1691 (2018-06-25)
Dysfunction of the glutamatergic system is believed to underlie many neurodevelopmental disorders including autism, Rett syndrome and schizophrenia. Metabotropic glutamate receptor (mGluR5) positive allosteric modulators (PAM) potentiate glutamatergic signaling, particularly indirectly via the NMDA receptor. Preclinical studies report mGluR5 PAMs
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