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重要文件

MAB5220

Sigma-Aldrich

Anti-NMDAR2B Antibody, clone 13A11

clone 13A11, Chemicon®, from mouse

同義詞:

NR2B

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

affinity purified immunoglobulin

無性繁殖

13A11, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

特異性

NMDAR2B

免疫原

Amino acid region 1033-1161 from human NMDAR2B produced as a GST fusion protein.

應用

Anti-NMDAR2B Antibody, clone 13A11 is an antibody against NMDAR2B for use in IC, IH & WB.
Immunohistochemistry (light and EM) on 4% paraformaldehyde & 0.125% glutaraldehyde fixed tissue: 2.5-5 μg/mL.

Immunocytochemistry: 2.5-5.0 μg/mL

Western blot: 1-5 μg/mL Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

外觀

Affinity purified immunoglobulin. Liquid in PBS. Contains no preservative.
Format: Purified

儲存和穩定性

Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Elisa A Waxman et al.
The Journal of biological chemistry, 282(24), 17594-17607 (2007-04-27)
The neuronal transporter excitatory amino acid carrier 1 (EAAC1) is enriched in perisynaptic regions, where it may regulate synaptic spillover of glutamate. In this study we examined potential interactions between EAAC1 and ionotropic glutamate receptors. N-Methyl-D-aspartate (NMDA) receptor subunits NR1
The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth.
Kim, MS; Chang, X; Nagpal, JK; Yamashita, K; Baek, JH; Dasgupta, S; Wu, G; Osada, M; Woo et al.
Oncogene null
Alexandre A Hoeller et al.
PloS one, 11(1), e0147293-e0147293 (2016-01-23)
Extensive evidence indicates the influence of the cholinergic system on emotional processing. Previous findings provided new insights into the underlying mechanisms of long-term anxiety, showing that rats injected with a single systemic dose of pilocarpine--a muscarinic receptor (mAChR) agonist--displayed persistent
Anteneh M Feyissa et al.
Progress in neuro-psychopharmacology & biological psychiatry, 33(1), 70-75 (2008-11-11)
Recent neuroimaging and postmortem studies have demonstrated abnormalities in glutamatergic transmission in major depression. Glutamate NMDA (N-methyl-d-aspartate) receptors are one of the major mediators of excitatory neurotransmission in the central nervous system. At synaptic sites, NMDA receptors are linked with

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