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重要文件

MAB4147

Sigma-Aldrich

Anti-MRP1 Antibody, clone MRPm5

clone MRPm5, Chemicon®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

tissue culture supernatant

抗體產品種類

primary antibodies

無性繁殖

MRPm5, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

同型

IgG2a

UniProt登錄號

運輸包裝

dry ice

基因資訊

human ... ABCC1(4363)

特異性

This antibody reacts with an internal epitope of MRP1, a 180-195 kDa transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. The antibody does not cross-react with the human MDR1 and MDR3 gene products.

免疫原

Bacterial fusion protein of MRP1 containing amino acids 986-1204 of the protein.

應用

Detect MRP1 using this Anti-MRP1 Antibody, clone MRPm5 validated for use in FC, WB, IH, IH(P).
Research Category
Metabolism
Research Sub Category
Toxicology & Drug Resistance
Western blotting

Immunohistochemistry: 1:20 on acetone fixed frozen tissue sections or paraffin-embedded tissue sections

Flow Cytometry

Optimal working dilutions must be determined by end user.

外觀

Format: Purified
Purified from tissue culture supernatant, serum-free. Liquid containing 0.7% BSA and 0.1% sodium azide.

儲存和穩定性

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. May be stored at 2-8°C for short term use. Avoid repeated freeze-thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer.
Nooter, K, et al.
Annals of Oncology, 7, 75-81 (1996)
Tissue distribution of the multidrug resistance protein.
Flens, M J, et al.
The American Journal of Pathology, 148, 1237-1247 (1996)
Prognostic significance of the immunohistochemical expression of O(6)-methylguanine-DNA methyltransferase, P-glycoprotein, and multidrug resistance protein-1 in glioblastomas.
Takao Nakagawa, Kazunori Ido, Takahiro Sakuma, Hiroaki Takeuchi, Kazufumi Sato et al.
Neuropathology : Official Journal of the Japanese Society of Neuropathology null
G L Scheffer et al.
Cancer research, 60(18), 5269-5277 (2000-10-04)
Tumor cells may display a multidrug resistance phenotype by overexpression of ATP binding cassette transporter genes such as multidrug resistance (MDR) 1 P-glycoprotein (P-gp) or the multidrug resistance protein 1 (MRP1). MDR3 P-gp is a close homologue of MDR1 P-gp

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