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Merck
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Key Documents

MAB3402C3

Sigma-Aldrich

抗GFAP抗体,Cy3偶联物

from mouse, CY3 conjugate

同義詞:

Glial fibrillary acidic protein, GFAP

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

共軛

CY3 conjugate

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

monoclonal

物種活性

mouse, pig

物種活性(以同源性預測)

porcine (based on 100% sequence homology), human (based on 100% sequence homology), rat (based on 100% sequence homology), chicken (based on 100% sequence homology)

技術

immunocytochemistry: suitable
immunohistochemistry: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... GFAP(2670)

一般說明

胶质纤维酸性蛋白是一种III类中间丝。GFAP是星形胶质细胞中间丝的主要成分,并且是一种细胞特异性标记,可在中枢神经系统发育过程中将分化的星形胶质细胞与其他神经胶质细胞区分开。

特異性

该抗体与小鼠GFAP反应。在组织切片中,该
抗体可染色星形胶质细胞和伯格曼神经胶质细胞(Debus,E.,1983)。

免疫原

纯化的神经胶质丝蛋白(Debus,E.,1983)。

應用

免疫组化分析:一个代表性批次以1:100的稀释度在成年小鼠脑组织中检测到GFAP。
抗GFAP抗体,Cy3结合物是用于IC,IH的针对GFAP的抗体。
研究子类别
发育神经科学
研究类别
神经科学

品質

通过免疫细胞化学评估分化的ReNcell VM.

免疫细胞化学分析:该抗体以1:100的稀释度可在分化的ReNcell VM中检测到GFAP。

標靶描述

观察到50 kDa(使用未偶联抗体MAB3402)

外觀

在含0.1%叠氮化钠和15 mg/mL BSA 的 PBS 中的Cy3偶联的纯化的小鼠单克隆 IgG1。
纯化的蛋白 A

儲存和穩定性

自收到之日起,以未稀释等分试样避光冷藏于 2-8°C,可保存6个月。

分析報告

对照
分化ReNcell VM

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Peng Lu et al.
Investigative ophthalmology & visual science, 63(3), 18-18 (2022-03-17)
Pituitary adenylate cyclase-activating polypeptide (PACAP) has shown potent neuroprotective effects in central nervous system and retina disorders. However, whether PACAP can attenuate retinal neurodegeneration induced by acute ocular hypertension (AOH) and the underlying mechanisms remain unknown. In this study, we
Junjin Lin et al.
Scientific reports, 11(1), 23569-23569 (2021-12-09)
Microvascular compression of the trigeminal root entry zone (TREZ) is the main cause of most primary trigeminal neuralgia (TN), change of glial plasticity was previously studied in the TREZ of TN rat model induced by chronic compression. To better understand
Galina Dvoriantchikova et al.
Scientific reports, 12(1), 17152-17152 (2022-10-14)
Ischemia-reperfusion (IR) injury is implicated in a large array of pathological conditions in the retina. Increasing experimental evidence suggests that programmed necrosis makes a significant contribution to inflammation and retinal damage triggered by IR. Since there are many types of
Stephen S Dominy et al.
Science advances, 5(1), eaau3333-eaau3333 (2019-02-13)
Porphyromonas gingivalis, the keystone pathogen in chronic periodontitis, was identified in the brain of Alzheimer's disease patients. Toxic proteases from the bacterium called gingipains were also identified in the brain of Alzheimer's patients, and levels correlated with tau and ubiquitin
Shahriar SheikhBahaei et al.
The Journal of comparative neurology, 526(13), 2032-2047 (2018-06-12)
Astrocytes, the most abundant and structurally complex glial cells of the central nervous system, are proposed to play an important role in modulating the activities of neuronal networks, including respiratory rhythm-generating circuits of the preBötzinger complex (preBötC) located in the

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