MAB312-AF647

Anti-A2B5 Antibody, clone A2B5-105 Antibody, Alexa Fluor^™ 647 Conjugate

clone A2B5-105, from mouse, ALEXA FLUOR^™ 647

• 同義詞: F12A2B5, 105
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• 共軛: ALEXA FLUOR^™ 647
• application: FACS; ICC
• 無性繁殖: A2B5-105, monoclonal
• 技術: flow cytometry: suitable; immunocytochemistry: suitable

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: ALEXA FLUOR^™ 647
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: A2B5-105, monoclonal
• 物種活性（以同源性預測）: mammals
• 技術: flow cytometry: suitable; immunocytochemistry: suitable
• 同型: IgM
• 運輸包裝: ambient
• 目標翻譯後修改: unmodified

描述

一般說明

A2B5 (also known as F12A2B5) is a cell surface ganglioside expressed on developing thymic epithelial cells, oligodendrocyte progenitors, and neuroendocrine cells. It is highly expressed in embryonic and neonatal tissue, but in the adult mammalian brain its expression is restricted mainly to areas that retain neurogenic potential, such as the subventricular zone (SVZ). Hence, A2B5 is considered as a marker for immature glial-committed precursors, which are permanently generated in the SVZ. Its expression is also considered as a marker for various cancers, including astrocytoma, glioma, pancreatic islet tumors, and squamous cell carcinoma. Explants from A2B5+ tumor cells display a typical progenitor morphology and clearly indicate their immature state. Tumors expressing A2B5 antigen exhibit higher rates of recurrence.

特異性

This monoclonal antibody detects A2B5 in mammalian cells.

免疫原

Embryonic chicken retinal cells.

應用

Anti-A2B5 Antibody, clone A2B5-105, Alexa Fluor^™ 647 Conjugate Cat. No. MAB312-AF647, is a highly specific mouse monoclonal antibody that targets A2B5 and has been tested in Immunocytochemistry and Flow Cytometry.

Flow Cytometry Analysis: 1:400 dilution from a representative lot immunostained the surface of PC12 cells.

The unconjugated antibody (Cat. No. MAB312) is also available for flow cytometry, immunocytochemistry, immunofluorescence, and immunohistochemistry applications.

品質

Evaluated by immunocytochemistry of PC12 cells.

Immunocytochemistry Analysis: A 1:100 Dilution of this antibody immunostained the surface of PC12 cells.

外觀

Purified mouse IgM Alexa Fluor^™ 647 conjugate in PBS with 1.5% BSA and 0.05% sodium azide.

其他說明

Concentration: Please refer to lot specific datasheet.

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2