MAB2609

Anti-beta Arrestin 1 Antibody, clone 3H11.2

clone 3H11.2, from mouse

• 同義詞: Retinal S-antigen, Rod photoreceptor arrestin, S-antigen, retina and pineal gland (arrestin), arrestin 1, retinal S-antigen (48 KDa protein)
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: saturated ammonium sulfate (SAS) precipitated
• 抗體產品種類: primary antibodies
• 無性繁殖: 3H11.2, monoclonal
• 物種活性: human
• 技術: immunofluorescence: suitable; western blot: suitable
• 同型: IgMκ
• NCBI登錄號: NP_004032.2
• UniProt登錄號: P49407
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ARRB1(408)

描述

一般說明

The Arrestin family consists of four members: Arrestin 1 (visual Arrestin), Arrestin 2 (beta Arrestin 1), Arrestin 3 (beta Arrestin 2), and Arrestin 4 (cone Arrestin). While visual and cone Arrestins are found almost exclusively in the retina, beta Arrestins 1 and 2 are ubiquitously expressed. Beta Arrestins appear to act as negative regulators on G protein-coupled receptors, (Lefkowitz, 1998). Interaction with molecules such as clathrin, AP-2 and NSF directs the clathrin-mediated internalization of G-protein-coupled receptors. Interaction with molecules such as Src, Raf, Erk, ASK1 and JNK3 appears to regulate several pathways that result in the activation of MAP kinases, (Lin, 1998; Miller, 2001).

特異性

Other species have not been tested.

Reacts with human beta-arrestin 1.

免疫原

Epitope: a.a. 357-372

KLH conjugated synthetic peptide corresponding to amino acids 357-372 of human beta arrestin 1.

應用

Anti-beta Arrestin 1 Antibody, clone 3H11.2 detects level of beta Arrestin 1 & has been published & validated for use in WB & IF.

Research Category
Cell Structure

Research Sub Category
Sensory & PNS

G-proteins

品質

Evaluated on a representative lot by Western blot in HEK293 cell lysate.

標靶描述

~47 kDa

外觀

Format: Purified

Purified in PBS with 0.05% NaN3.

儲存和穩定性

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

分析報告

Control
HEK293 cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable