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Key Documents

MAB1564

Sigma-Aldrich

Anti-Serotonin Transporter Antibody, clone 17-7A4

clone 17-7A4, Chemicon®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

17-7A4, monoclonal

物種活性

rat

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable

同型

IgG1

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

特異性

Recognizes Serotonin Transporter.

免疫原

Rat serotonin transporter, N-terminus/GST fusion protein (aa 1-85).

應用

Detect Serotonin Transporter using this Anti-Serotonin Transporter Antibody, clone 17-7A4 validated for use in IH.
Immunohistochemistry: 0.5-1.0 μg/mL on paraformaldehyde fixed brain and adrenal tissue. Has not been tested on paraffin embedded tissue. Not recommended for use in Western blotting. Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers

外觀

Protein A purified
Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.

儲存和穩定性

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

分析報告

Control
Brain tissue

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Modulation of the trafficking of the human serotonin transporter by human alpha-synuclein.
Christophe Wersinger, Milan Rusnak, Anita Sidhu
The European Journal of Neuroscience null
P Brown et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 20(5), 1952-1963 (2000-02-24)
Dopamine release in the nucleus accumbens (NAc) has been implicated as mediating the rewarding effects of stimulant drugs; however, recent studies suggest that 5-HT release may also contribute. In an effort to assess the role of 5-HT in drug-mediated reward
A L Halberstadt et al.
Neuroscience, 147(1), 207-223 (2007-05-18)
It is well known that the dorsal raphe nucleus (DRN) sends serotonergic and nonserotonergic projections to target regions in the brain stem and forebrain, including the vestibular nuclei. Although retrograde tracing studies have reported consistently that there are differences in
Coexpression of serotonin and nitric oxide in the raphe complex: cortical versus subcortical circuit.
Yuefeng Lu,Kimberly L Simpson,Kristin J Weaver,Rick C S Lin
Anatomical Record (Hoboken, N.J. : 2007) (2007)
Normal development of serotonergic neurons in mice lacking S100B.
Hiroshi Nishiyama, Masaaki Takemura, Takehiro Takeda, Shigeyoshi Itohara
Neuroscience Letters null

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