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Merck
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Key Documents

GF309

Sigma-Aldrich

NT-4 Protein, Human Recombinant Animal Free

The Neurotrophin-4 protein (or NT-4 protein), also known as NT-5 protein, is a member of the NGF family of neuronal & epithelial growth factors.

同義詞:

NT4, Neurotrophin 4, Neurotrophin 4/5, NT4/5

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.77

品質等級

化驗

>98% (SDS-PAGE and HPLC)

雜質

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

一般說明

Neurotrophin4 (NT4), also known as NT5, is a member of the NGF family of neuronal and epithelial growth factors. NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).

特異性

Cross Reactivty
Mouse, Rat

品質

Bioactivity assay: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.

外觀

Recombinant animal free human NT-4 is manufactured using all non-animal reagents

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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