GF303

G-CSF Protein, Human Recombinant Animal Free

The GCSF protein is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation & activation of hematopoietic cells of the neutrophilic granulocyte lineage. Manufactured using all non-animal reagents.

• 同義詞: GCSF, Granulocyte Colony Stimulating Factor, Pluripoietin, Filgrastim, Lenograstim
• 分類程式碼代碼: 12352202
• eCl@ss: 32160405
• NACRES: NA.75

屬性

• 品質等級: 100
• 化驗: >98% (SDS-PAGE and HPLC)
• 雜質: <0.1 μg/mg protein endotoxin (<1EU/μg)
• NCBI登錄號: NM_000759.42; NM_172219.1; NM_172220.1
• UniProt登錄號: P09919
• 運輸包裝: dry ice

描述

一般說明

Granulocyte Colony-Stimulating Factor (GCSF) is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation, and activation of hematopoietic cells of the neutrophilic granulocyte lineage. It is produced mainly by monocytes and macrophages upon activation by endotoxin, TNFα and IFNγ. Other cell types including fibroblasts endothelial cells, astrocytes and bone marrow stromal cells can also secrete GCSF after LPS, IL1 or TNFα activation. In addition, various carcinoma cell lines and myeloblastic leukemia cells can express GCSF constitutively. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.

Product Source: E. coli

特異性

Cross Reactivty
Mouse

應用

Research Category
Inflammation & Immunology

Research Sub Category
Growth Factors & Receptors

包裝

10 ug

品質

Bioactivity assay: Determined by its ability to stimulate the proliferation of mouse M-NFS-60 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

外觀

Product is filtered through a 0.2 micron filter before lyophilization.

Recombinant animal free human G-CSF is manufactured using all non-animal reagents

儲存和穩定性

Store at -20°C for up to 6 months from date of receipt.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1