FCMAB195F

Milli-Mark^® Anti-CD41-FITC Antibody, clone 5B12

clone 5B12, Milli-Mark^®, from mouse

• 同義詞: Integrin alpha-IIb, Platelet membrane glycoprotein IIb, GPalpha IIb, GPIIb
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.44
• 共軛: FITC conjugate
• application: FACS
• 無性繁殖: 5B12, monoclonal
• 物種活性: human
• citations: 2
• 技術: flow cytometry: suitable

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: FITC conjugate
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 5B12, monoclonal
• 物種活性: human
• 製造商／商標名: Milli-Mark^®
• 技術: flow cytometry: suitable
• 同型: IgG1κ
• NCBI登錄號: NP_000410
• UniProt登錄號: P08514
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ITGA2B(3674)

描述

一般說明

CD41 is the α-subunit of the CD41/CD61 complex (GPIIb-IIIa), a calcium-dependent, non-covalently associated heterodimer. CD41 is a 135 kDa molecule, consisting of 2 peptides: a 120 kDa α chain and a 23 kDa β chain. The α chain and the β chain are linked by a single disulphide bond. The α chain contains four calcium-binding sites and is entirely extracellular, while the β-chain has extracellular, transmembrane, and cytoplasmic domains (Sun, 1997). The CD41/CD61 complex appears early in megakaryocyte maturation (Vinci, 1984). Anti-CD41, 5B12, was included in the Fifth International Workshop and Conference on Human Leukocyte Differentiation Antigens and studies by a number of laboratories confirmed its reactivity with CD41 (Honda, 1995).

特異性

Antibody recognizes Human CD41 antigen.

免疫原

Normal human platelets

應用

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

This Milli-Mark Anti-CD41-FITC Antibody, clone 5B12 is validated for use in FC for the detection of CD41.

品質

Evaluated by flow cytometry using TF-1 cells

標靶描述

135 kDa (Sun, 1997)

外觀

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

儲存和穩定性

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

分析報告

Control
TF-1 cells

法律資訊

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable