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Merck
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重要文件

ECM445

Sigma-Aldrich

β1 Integrin Partners Kit

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.41

物種活性

human

品質等級

製造商/商標名

Chemicon®

技術

ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

基因資訊

human ... ITGB1(3688)

一般說明

Chemicon Investigator Kits for Integrin Research are a cost-effective source of reagents for all investigators intimately involved with this expanding field of study. The beta1 Integrin Partners Investigator Kit is designed for research focused on the human beta1 integrin subunit and those integrin subunits known to pair with beta1, including alpha1, alpha2, alpha3, alpha4, alpha5, alpha6 and alphaV.

Integrins belong to a large family of cell surface proteins commonly referred to as glycoproteins. Integrins are composed of noncovalently associated alpha and beta subunits which make up heterodimers: the larger termed alpha chain and the smaller beta chain. At least 16 alpha subunits and 8 beta subunits are expressed, which can give rise to 22 different integrins. Integrins are thought to play critical roles in cell migration, differentiation, and survival. There is now considerable evidence that these transmembrane receptors play an important role in the regulation of gene expression and signal transduction. Excellent reviews of integrin structure, function, and ligand specificity may be found in: Hynes, R. 1992. Cell 69:11-25; Kramer, R. 1993. "Integrin Structure and Ligand Specificity in Cell-Matrix Interactions" in Molecular and Cellular Aspects of Basement Membranes. Academic Press.

Chemicon offers the b1 Integrin Partners Investigator Kit for initial studies of b1 subunit interactions. All kit reagents are also available in larger sizes. The reagents in this kit are not application specific but rather may be used in a variety of procedures, depending upon the needs of the individual investigator.

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應用

Research Category
Cell Structure
Research Sub Category
Integrins

成分

beta1 Mouse Monoclonal Antibody (Part No. MAB1951Z-20)- 1 tube, 20 μg.

alpha1 Mouse Monoclonal Antibody (Part No. MAB1973Z-20) - 1 tube, 20 μg.

alpha2 Mouse Monoclonal Antibody (Part No. MAB1950Z-20)- 1 tube, 20 μg.

alpha3 Mouse Monoclonal Antibody (Part No. MAB1952Z-20) - 1 tube, 20 μg.

alpha4 Mouse Monoclonal Antibody (Part No. MAB16983Z-20) - 1 tube, 20 μg.

alpha5 Mouse Monoclonal Antibody (Part No. MAB 1956Z-20) - 1 tube, 20 μg.

alpha6 Rat Monoclonal Antibody (Part No. MAB1378-20)- 1 tube, 20 μg.

alphaV Mouse Monoclonal Antibody (Part No. MAB1953Z-20)- 1 tube, 20 μg.

外觀

With 20 μg each of monoclonals to alpha1, alpha2, alpha3, alpha4, alpha5, alpha6, alphaV, and beta1. Chemicon′s beta1 Integrin Kit (ECM445) provides a cost-effective means to study the beta1 integrin and its associated alpha subunits.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

儲存類別代碼

10 - Combustible liquids


分析證明 (COA)

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