CBL1348

Anti-Integrin beta1 Antibody, clone HM beta 1.1

clone HM beta 1.1, from hamster

• 同義詞: CD29 antigen, Fibronectin receptor subunit beta, Integrin VLA-4 subunit beta, fibronectin receptor beta subunit, integrin VLA-4 beta subunit, integrin beta 1, integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen ; ; CD29 includes MDF2,
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: hamster
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: HM beta 1.1, monoclonal
• 物種活性: human, mouse
• 技術: immunocytochemistry: suitable
• 同型: IgG
• NCBI登錄號: NP_002202.2
• UniProt登錄號: P09055
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ITGB1(3688) ; mouse ... Itgb1(16412)

描述

一般說明

Integrin beta 1is also known as CD29. It is a transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits, forming the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions such as hemostasis, embryonic development, wound repair, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. These heterodimeric receptors bridge the cytoplasmic actin cytoskeleton with proteins present in the extracellular matrix and on adjacent cells. The clustering of integrins on a cell surface leads to the formation of focal contacts. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression. Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion.

特異性

Other species have not been tested.

免疫原

Epitope: Full length

Purified mouse VLA-4 antigen

應用

Detect Integrin beta1 using this Anti-Integrin beta1 Antibody, clone HM beta 1.1 validated for use in IC.

Research Category
Cell Structure

Research Sub Category
Integrins

品質

Routinely evaluated by immunocytochemistry on mouse NIH3T3, A431 cells.

標靶描述

130 kDa

外觀

Protein G Purified

Format: Purified

Purified in PBS with 0.05% NaN3.

儲存和穩定性

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

分析報告

Control
NIH3T3, A431

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable