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重要文件

CBL173

Sigma-Aldrich

Anti-Desmoplakin 1& 2 Antibody, clone DP2.15

clone DP2.15, Chemicon®, from mouse

同義詞:

Anti-DCWHKTA, Anti-DP

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

DP2.15, monoclonal

物種活性

bovine, human, chicken, rat, mouse

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable

同型

IgG1

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... DSP(1832)

特異性

This antibody shows distinct punctate membrane staining of desmoplakins 1 (MW 250 kDa) and 2 (MW 215 kDa) in stratified epithelia and simple epithelia, including glands, urothelium, thymic reticular epithelium, hepatocytes, intercalated disks of myocardium and arachnoid cells of meninges.

免疫原

Bovine desmoplakin 1 & 2

應用

Anti-Desmoplakin 1& 2 Antibody, clone DP2.15 detects level of Desmoplakin 1& 2 & has been published & validated for use in IF, WB & IC.
Research Category
Cell Structure
Research Sub Category
Cytoskeleton
Western blot
Immunohistochemistry: 1:10; Frozen tissue
Immunofluorescence

Optimal working dilutions must be determined by the end user.

外觀

Format: Purified
Lyophilized. Reconstitute in 1 mL distilled water (final solution contains 0.09% sodium
azide, 0.5% BSA in PBS buffer, pH 7.4

儲存和穩定性

Reconstituted antibody can be stored at 2°-8°C for up to 12 months from date of receipt. Antibody can also be stored at -20°C in undiluted aliquots.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Immunocytochemical identification of epithelium-derived human tumors with antibodies to desmosomal plaque proteins.
Franke, W W, et al.
Proceedings of the National Academy of Sciences of the USA, 80, 543-547 (1983)
Annika Gross et al.
Cellular and molecular gastroenterology and hepatology, 13(4), 1181-1200 (2021-12-21)
Desmosomes are intercellular junctions connecting keratin intermediate filaments of neighboring cells. The cadherins desmoglein 2 (Dsg2) and desmocollin 2 mediate cell-cell adhesion, whereas desmoplakin (Dsp) provides the attachment of desmosomes to keratins. Although the importance of the desmosome-keratin network is
Wenxiu Ning et al.
Cell stem cell, 28(3), 436-452 (2020-12-03)
Basal stem cells fuel development, homeostasis, and regeneration of the epidermis. The proliferation and fate decisions of these cells are highly regulated by their microenvironment, including the basement membrane and underlying mesenchymal cells. Basal progenitors give rise to differentiated progeny

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