ABT334

Anti-TSLP receptor Antibody

from rabbit, purified by affinity chromatography

• 同義詞: TSLP Receptor Antibody, TSLP Receptor, Thymic stromal lymphopoietin receptor, CRL2, ILXR, TSLPR, Cytokine receptor-like factor 2, Cytokine receptor-like 2, IL-XR
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• 無性繁殖: polyclonal
• application: IF; IHC; WB
• 物種活性: human
• 技術: immunofluorescence: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: immunofluorescence: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• UniProt登錄號: Q9HC73
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... TSLP(85480)

描述

一般說明

Thymic stromal lymphopoietin (TSLP) receptor is a member of the Type I cytokine receptor family (type 5 subfamily). TSLP has been shown to play an important role in dendritic cell maturation and activation. Additionally, TSLP receptor is involved in the positive selection of regulatory T cells, induction of CD4+ T cell-mediated allergic reaction and maintenance of peripheral CD4+ T cell homeostasis. Furthermore, TSLP receptor is implicated in the development of the hematopoietic system. TSLP receptor forms a functional complex with TSLP receptor and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. TSLP receptor is primarily expressed in dendrites and monocytes. Additionally, it is expressed in heart, skeletal muscle, kidney and adult and fetal liver; and weakly expressed in T-cells.

免疫原

KLH-conjugated linear peptide corresponding to human TSLP receptor.

應用

Detect TLSP Receptor using this rabbit polyclonal antibody, Anti-TSLP receptor Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected TSLP receptor in human liver tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TSLP receptor in human liver cells.

Research Category
Signaling

Research Sub Category
Cytokines & Cytokine Receptors

品質

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected TSLP receptor in 15 µg of human liver tissue lysate.

標靶描述

~53 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~27 kDa and ~42 kDa

外觀

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Human liver tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable