ABN297

Anti-Oxytocin receptor Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Oxytocin receptor, OT-R
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: mouse, human
• 技術: western blot: suitable
• NCBI登錄號: NP_000907
• UniProt登錄號: P30559
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... OXTR(5021)

描述

一般說明

Oxytocin is a cyclic 9 amino acid peptide that differs from vasopressin in 2 amino acids. Despite the close similarities in sequence, oxytocin and vasopressin have different biological activities and bind to distinct G protein-coupled receptors. The oxytocin receptor, OT, couples primarily to Gq/11 to mobilize intracellular calcium. In female reproduction, oxytocin promotes uterine contraction and lactation; oxytocin is the most commonly used drug for induction of labor, whereas an oxytocin antagonist, atosiban, is under investigation to suppress preterm labor. Oxytocin/OT interaction in the CNS also plays an important role in stress, male and female sexual response, and sociality.

免疫原

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Oxytocin receptor.

應用

Anti-Oxytocin receptor Antibody is a highly specific rabbit polyclonal antibody, that targets Oxytocin Receptor & has been tested in western blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting in MCF7 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Oxytocin receptor in 10 µg of MCF7 cell lysate.

標靶描述

~45/65 kDa observed The calculated molecular weight of this protein is 43 kDa However, this protein has been observed at ~60-70 kDa due to glycoslyatation (Zhong, M.m et al. (2012). Molecular Cancer Research. 1-25). Uncharacterized band(s) may appear in some lysates.

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable