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Merck
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Key Documents

ABN278

Sigma-Aldrich

抗Prospero同源盒蛋白1/PROX1抗体

from rabbit, purified by affinity chromatography

同義詞:

Prospero homeobox protein 1, Homeobox prospero-like protein PROX1, PROX-1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

mouse, rat

物種活性(以同源性預測)

bovine (based on 100% sequence homology), fish (based on 100% sequence homology), chicken (based on 100% sequence homology), human (based on 100% sequence homology)

技術

immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Prox1(19130)

一般說明

PROX1(Prospero同源盒蛋白1)是果蝇Prospero的同源物,是一种含有同源盒的转录因子,可结合并充当肝受体同源物1(LRH1/NR5A2)的共受体。它是淋巴内皮细胞以及成肝细胞和肝细胞的特异性标志物。人Prox1与小鼠和大鼠Prox1具有97%的氨基酸序列一致性。

免疫原

KLH偶联的线性肽,对应于人Prospero同源盒蛋白1/PROX1的C末端。

應用

免疫组化分析:代表性批次的1:2,000的稀释液在小鼠E16胚胎丘脑组织中检测到Prospero同源盒蛋白1/PROX1(Prof. Samual Pleasure, University of California, San Francisco.)。

Alexa Fluor是Life Technologies,Inc.的注册商标。
该抗Prospero同源盒蛋白1/PROX1抗体经验证可用于蛋白质印迹&IHC检测Prospero同源盒蛋白1/PROX1。

品質

通过蛋白质印迹在HEK293核提取物中进行了评估。

蛋白质印迹分析:该抗体的1:500稀释液在10 µg HEK293核提取物中检测到Prospero同源盒蛋白1/Prox1。

標靶描述

观察值〜95 kDa。Uniprot描述了83kDa的分子量,然而,由于SUMO化和/或替代起始位点,可在80-110kDa之间观察到该蛋白(Pan,M.R.,et al.(2009).J Cell Sci. 122(Pt18):3358-3361.; Azuma, K., et al. (2011).Genes Cells.16(11):1063-1070.)。

聯結

替代品:AB5475

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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