ABE55

Anti-Maf-B Antibody

serum, from rabbit

• 同義詞: v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian), MAFB/Kreisler basic region/leucine zipper transcription factor, transcription factor MafB, Kreisler (mouse) maf-related leucine zipper homolog, Kreisler maf-related leucine zipper homolog
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: serum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: rat, mouse, human
• 技術: immunocytochemistry: suitable; western blot: suitable
• 同型: IgG
• NCBI登錄號: NP_005452
• UniProt登錄號: Q9Y5Q3
• 運輸包裝: dry ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MAFB(9935)

描述

一般說明

Transcription factor MafB (Maf-B) belongs to the bZIP family as a part of the MAF subfamily and contains a characteristic bZIP domain. Maf-B can function as either a transcriptional activator or repressor. It regulates erythroid differentiation through its interaction with and negative regulation of EST-1 activity. Maf-B is a critical factor in the differentiation of islet beta cells, alpha and beta cells, macrophage, monocytic, and podocyte cells. It is involved in macrophage expression and maturation of F4/80, and regulates renal development and survival of renal tubules. Interaction with SUMO regulates the transcriptional activity of Maf-B along with its function in determining macrophage fate. Studies have shown that, relative to cell context, Maf-B can act as either a tumor or an oncogene suppressor.

免疫原

KLH-conjugated linear peptide corresponding to human Maf-B.

應用

Anti-Maf-B Antibody is a Rabbit Polyclonal Antibody for detection of Maf-B also known as v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) & has been validated in WB, ICC.

Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected Maf-B in NIH/3T3 cells.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Transcription Factors

品質

Evaluated by Western Blot in L6 cell lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected Maf-B on 10 µg of L6 cell lysate.

標靶描述

~ 36 kDa observed

外觀

Unpurified

Rabbit polyclonal serum containing 0.05% sodium azide

儲存和穩定性

Store at -20°C
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析報告

Control
L6 cell lysate

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1