ABE335

Anti-FOXL2 Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Forkhead box protein L2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 物種活性（以同源性預測）: porcine (based on 100% sequence homology), rabbit (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology)
• 技術: western blot: suitable
• NCBI登錄號: NP_075555
• UniProt登錄號: P58012
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified

描述

一般說明

Forkhead box protein L2 (FOXL2) is a fork-head transcription factor that is expressed in developing gonad and in granulosa cells of the mature ovary. It plays a role in repressing the development of testis, and facilitating the differentiation and maintenance of the ovary. Mutations in the FOXL2 gene result in blepharophimosis ptosis epicanthus inversus (BPES) syndrome, which is characterized by craniofacial defects and premature ovarian failure. FOXL2 has also been implicated in the development of ovarian granulosa cell tumors.

特異性

Other homologies: Chicken (77% sequence homology).

免疫原

KLH-conjugated linear peptide corresponding to human FOXL2.

應用

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

This Anti-FOXL2 Antibody is validated for use in Western Blotting for the detection of FOXL2.

品質

Evaluated by Western Blot in human pituitary tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected FOXL2 in 10 µg of human pituitary tissue lysate.

標靶描述

~50 kDa observed. An uncharacterized band may appear at ~25 kDa in some lysates. The calculated molecular weight is 39 kDa, however FOXL2 has been shown as a ~50 kDa band in western blots (Marongiu, M., et al. (2010). PLOS One. 5(3):1-9).

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Human pituitary

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable