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Key Documents

AB5779

Sigma-Aldrich

Anti-Striatin Antibody

serum, Chemicon®

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse, human, rat

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... STRN(6801)

一般說明

Striatin is found in all mammalian cells and may be involved in vesicular transport, dendrite growth and cellular signalling. It binds Protein phosphatase 2A (PP2A) A and C subunits and calmodulin and appears to modulate PP2A activity. It also binds the human homolog of the yeast protein, Mob1, which has been implicated in mitotic progression in yeast. It is a member of a family of proteins that also include SG2NA (striatin 3) and Zinedin (striatin 4).

特異性

Reacts with Striatin. No cross reactivity with SG2NA.

免疫原

Synthetic Striatin peptide.

應用

Anti-Striatin Antibody detects level of Striatin & has been published & validated for use in IP, WB & IC.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Western blot: 1:500-1:1,000. The antibody reacts with the ~110 kDa striatin protein in 293 cell lysate.

Immunocytochemistry: 1:500

Immunoprecitation: 3 μL recommended as starting point.

Optimal working dilutions must be determined by the end user.

外觀

Rabbit serum. Liquid containing 40% glycerol and 0.02% sodium azide.

儲存和穩定性

Maintain at -20°C in undiluted for up to 12 months after date of receipt. For long-term storage, may be stored at -80°C. Avoid repeated freeze/thaw cycles at temperatures below -20°C.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Vincent Ricchiuti et al.
The Journal of endocrinology, 211(1), 47-54 (2011-07-13)
Liberal or high-sodium (HS) intake, in conjunction with an activated renin-angiotensin-aldosterone system, increases cardiovascular (CV) damage. We tested the hypothesis that sodium intake regulates the type 1 angiotensin II receptor (AT(1)R), mineralocorticoid receptor (MR), and associated signaling pathways in heart
X X Yu et al.
Molecular biology of the cell, 12(1), 185-199 (2001-02-13)
Binding of different regulatory subunits and methylation of the catalytic (C) subunit carboxy-terminal leucine 309 are two important mechanisms by which protein phosphatase 2A (PP2A) can be regulated. In this study, both genetic and biochemical approaches were used to investigate
C S Moreno et al.
The Journal of biological chemistry, 275(8), 5257-5263 (2000-02-22)
Protein phosphatase 2A (PP2A) is a multifunctional serine/threonine phosphatase that is critical to many cellular processes including development, neuronal signaling, cell cycle regulation, and viral transformation. PP2A has been implicated in Ca(2+)-dependent signaling pathways, but how PP2A is targeted to
Sean E Thatcher et al.
Biology of sex differences, 6, 12-12 (2015-07-02)
Abdominal aortic aneurysms (AAAs) occur predominately in males. However, AAAs in females have rapid growth rates and rupture at smaller sizes. Mechanisms contributing to AAA progression in females are undefined. We defined effects of ovariectomy, with and without 17-β estradiol

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