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Merck
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Key Documents

AB4326

Sigma-Aldrich

ISL-1抗体

from rabbit, purified by affinity chromatography

同義詞:

ISL LIM homeobox 1, ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain, (islet-1)

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

horse, human, mouse

物種活性(以同源性預測)

sheep (based on 100% sequence homology), canine (based on 100% sequence homology), rat (based on 100% sequence homology), equine (based on 100% sequence homology), bovine (based on 100% sequence homology)

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ISL1(3670)

一般說明

胰岛因子1(ISL-1)是一种转录因子,在朗格汉斯胰岛的胚胎发生中发挥重要作用。它在肾上腺髓质和背根神经节的神经元亚群、视网膜内核和神经节细胞层、松果体和大脑某些区域中表达。在小鼠胚胎中,缺乏这种基因就无法进行神经管运动神经元的分化。最近,它被确定为心脏祖细胞谱系的标志物,该谱系能够分化为所有3种主要心脏细胞类型:心肌细胞、平滑肌和内皮细胞谱系。

特異性

基于100%的序列同源性,预测会与最常见的脊椎动物物种反应。
该抗体可识别ISL-1。

免疫原

KLH偶联线性肽,对应于人ISL-1。
表位:ISL-1的内部区域。

應用

ISL-1抗体是一种检测ISL-1(又称ISL LIM同源盒1、ISL1转录因子LIM/同源结构域)的兔多克隆抗体 & 已通过WB & IHC验证。
免疫组化分析:先前批次的1:300稀释液在小鼠胰腺组织中检测到ISL-1。

品質

通过蛋白质印迹法对K562细胞裂解液进行了评估。

蛋白质印迹分析:0.5 µg/mL的该抗体在10 µg K562细胞裂解液中检测到ISL-1。

標靶描述

~39 kDa

其他說明

浓度:请参考批次特异性浓缩物的检验报告。

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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