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Merck
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Key Documents

AB153-I

Sigma-Aldrich

抗荧光金抗体

from rabbit

同義詞:

Fluorescent Marker

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性(以同源性預測)

all

技術

immunohistochemistry: suitable (paraffin)

運輸包裝

wet ice

目標翻譯後修改

unmodified

一般說明

荧光金(羟基芪脒),又称Fluorogold,已成为一种非常流行的荧光标记物,用于逆行标记投射神经元。在冷冻的4%PFA固定组织中,AB153还可以与氨基芪脒很好地反应。

特異性

该抗体将与经荧光金处理的任何种属样品反应。

免疫原

KLH偶联的荧光金。

應用

免疫组化分析:来自独立实验室的代表性批次在大鼠额叶皮层组织中检测到荧光金处理的神经元(Chang, H. T., et al. (1990).J Neurosci Methods.35(1):31-37.)。
抗荧光金抗体是高度特异性的兔多克隆抗体,靶向Fluoro-Gold & 已在IHC(石蜡)中进行了测试。

品質

通过免疫组化在固定冷冻的荧光金处理的大鼠大脑皮层组织中进行评估。

免疫组织化学分析:该抗体的1:10,000稀释液在固定的冷冻荧光金处理的大鼠大脑皮层组织中检测到荧光金。

外觀

形式:纯化

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Sofia Meyer Zu Reckendorf et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 42(12), 2474-2491 (2022-02-13)
In postmitotic neurons, several tumor suppressor genes (TSGs), including p53, Rb, and PTEN, modulate the axon regeneration success after injury. Particularly, PTEN inhibition is a key driver of successful CNS axon regeneration after optic nerve or spinal cord injury. In
Chang-Hui Chen et al.
Frontiers in neuroscience, 15, 772016-772016 (2021-11-20)
Area prostriata is a limbic structure critical to fast processing of moving stimuli in far peripheral visual field. Neural substrates underlying this function remain to be discovered. Using both retrograde and anterograde tracing methods, the present study reveals that the
Nóra Hádinger et al.
Nature neuroscience, 26(1), 116-130 (2022-12-23)
Corticothalamic pathways, responsible for the top-down control of the thalamus, have a canonical organization such that every cortical region sends output from both layer 6 (L6) and layer 5 (L5) to the thalamus. Here we demonstrate a qualitative, region-specific difference
Martín Macías et al.
Frontiers in human neuroscience, 16, 1043501-1043501 (2022-12-13)
The ability to learn motor skills implicates an improvement in accuracy, speed and consistency of movements. Motor control is related to movement execution and involves corticospinal neurons (CSp), which are broadly distributed in layer 5B of the motor and somatosensory
Patrick Lüningschrör et al.
Cell reports, 30(10), 3506-3519 (2020-03-12)
Genetic variations in TMEM106B, coding for a lysosomal membrane protein, affect frontotemporal lobar degeneration (FTLD) in GRN- (coding for progranulin) and C9orf72-expansion carriers and might play a role in aging. To determine the physiological function of TMEM106B, we generated TMEM106B-deficient

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