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Merck
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Key Documents

8.55140

Sigma-Aldrich

Fmoc-PAL-Linker

Novabiochem®

同義詞:

Fmoc-PAL-Linker

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About This Item

經驗公式(希爾表示法):
C29H31NO7
CAS號碼:
分子量::
505.56
分類程式碼代碼:
12352209
NACRES:
NA.22

品質等級

產品線

Novabiochem®

形狀

solid

反應適用性

reagent type: linker

製造商/商標名

Novabiochem®

mp

178-180 °C

應用

peptide synthesis

官能基

Fmoc

儲存溫度

2-8°C

InChI

1S/C29H31NO7/c1-34-26-15-19(36-14-8-7-13-28(31)32)16-27(35-2)24(26)17-30-29(33)37-18-25-22-11-5-3-9-20(22)21-10-4-6-12-23(21)25/h3-6,9-12,15-16,25H,7-8,13-14,17-18H2,1-2H3,(H,30,33)(H,31,32)

InChI 密鑰

ATYUCXIJDKHOPX-UHFFFAOYSA-N

一般說明

Barany′s aminomethyl-dimethoxyphenoxyvaleric acid linker [1]. The amino group of this linker can be easily acylated under standard coupling conditions. Following peptide assembly, treatment with 95% TFA containing scavengers releases the desired peptide amide. Studies have shown the acid sensitivity of this linker to be around twice that of the Rink amide linker [2]. There is some evidence to suggest that PAL resins give greater yields in microwave assisted synthesis.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

分析報告

Color (visual): white to beige to grey
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(0811)): ≥ 98.0 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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