推薦產品
品質等級
產品線
Novabiochem®
形狀
beads
反應適用性
reaction type: Fmoc solid-phase peptide synthesis
製造商／商標名
Novabiochem®
應用
peptide synthesis
官能基
aldehyde
儲存溫度
2-8°C
一般說明
This resin is prepared under conditions optimized to minimize styrene formation during attachment of the linker to the functionalized ethylpolystyrene support. This high substitution, coupled with the lack of amide bonds and potentially acid-sensitive benzylic linkages, makes this support the preferred choice of SPOS of secondary sulfonamides and carboxamides. Applications of FMPE include aminofurazanopyrazines [1] and peptide agonists for human orphan receptor BRS-3 [2].
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins Literature references
Literature references
[1] B. Dörner & P. White in ′Peptides 1998, Proc. 25th European Peptide Symposium′, S. Bajusz & F. Hudecz (Eds), Budapest, Akadémiai Kiadó, 1999, pp. 90.
[2] M. Grimstrup & F. Zaragoza (2002) Eur. J. Org. Chem., 2953.
[3] K. J. Jensen, et al. (1998) J. Am. Chem. Soc., 120, 5441.
[4] M. del Fresno, et al. (1998) Tetrahedron Lett., 39, 2639.
[5] N. S. Gray, et al. (1997) Tetrahedron Lett., 38, 1161.
[6] J. Alsina, et al. (1999) Chem. Eur. J., 5, 2787.
[7] J. F. Tolborg & K. J. Jensen (2000) Chem. Commun., 147.
[8] A. E. Fenwick, et al. (2001) Bioorg. Med. Chem. Lett., 11, 195.
[9] J. Giovannoni, et al. (2001) Tetrahedron Lett., 42, 5389.
[10] J. T. Bork, et al. (2003) Org. Lett., 5, 117.
[11] C. P. Holmes, Paper ORGN 383 presented at the 213th National Meeting of the American Chemical Society, San Francisco, 1997.
[12] C. Pégurier, et al. (2000) Bioorg. Med. Chem., 8,163.
[13] T. F. Herpin, et al. (2000) J. Comb. Chem., 2, 513.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins Literature references
Literature references
[1] B. Dörner & P. White in ′Peptides 1998, Proc. 25th European Peptide Symposium′, S. Bajusz & F. Hudecz (Eds), Budapest, Akadémiai Kiadó, 1999, pp. 90.
[2] M. Grimstrup & F. Zaragoza (2002) Eur. J. Org. Chem., 2953.
[3] K. J. Jensen, et al. (1998) J. Am. Chem. Soc., 120, 5441.
[4] M. del Fresno, et al. (1998) Tetrahedron Lett., 39, 2639.
[5] N. S. Gray, et al. (1997) Tetrahedron Lett., 38, 1161.
[6] J. Alsina, et al. (1999) Chem. Eur. J., 5, 2787.
[7] J. F. Tolborg & K. J. Jensen (2000) Chem. Commun., 147.
[8] A. E. Fenwick, et al. (2001) Bioorg. Med. Chem. Lett., 11, 195.
[9] J. Giovannoni, et al. (2001) Tetrahedron Lett., 42, 5389.
[10] J. T. Bork, et al. (2003) Org. Lett., 5, 117.
[11] C. P. Holmes, Paper ORGN 383 presented at the 213th National Meeting of the American Chemical Society, San Francisco, 1997.
[12] C. Pégurier, et al. (2000) Bioorg. Med. Chem., 8,163.
[13] T. F. Herpin, et al. (2000) J. Comb. Chem., 2, 513.
聯結
Replaces: 01-64-0360
分析報告
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined by elemental analysis of sulfur after derivatization with tosylhydrazide): 0.50 - 1.10 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene-1 % DVB), 100 -200 mesh
Appearance of substance (visual): beads
Loading (determined by elemental analysis of sulfur after derivatization with tosylhydrazide): 0.50 - 1.10 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene-1 % DVB), 100 -200 mesh
法律資訊
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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