8.52360

Fmoc-L-propargylglycine

Novabiochem^®

• 同義詞: Fmoc-L-propargylglycine, N-Fluorenemethoxycarbonyl-L-propargyl glycine
• 經驗公式（希爾表示法）: C₂₀H₁₇NO₄
• CAS號碼: 198561-07-8
• 分子量：: 335.35
• MDL號碼: MFCD01075095
• 分類程式碼代碼: 12352209
• NACRES: NA.22

屬性

• 品質等級: 200
• 產品線: Novabiochem^®
• 形狀: solid
• 反應適用性: reaction type: Fmoc solid-phase peptide synthesis
• 製造商／商標名: Novabiochem^®
• 應用: peptide synthesis
• 官能基: alkyne
• 儲存溫度: 15-25°C
• InChI: 1S/C20H17NO4/c1-2-7-18(19(22)23)21-20(24)25-12-17-15-10-5-3-8-13(15)14-9-4-6-11-16(14)17/h1,3-6,8-11,17-18H,7,12H2,(H,21,24)(H,22,23)/t18-/m0/s1
• InChI 密鑰: DJGMNCKHNMRKFM-SFHVURJKSA-N

描述

一般說明

Building block for the introduction by Fmoc SPPS of an amino acid bearing an alkyne side chain. Such derivatives are useful tools for the synthesis of cyclic peptides by an alkyne-alkyne Glaser coupling, involving Cu(OAc)₂/pyridine and heating to 60 °C using microwaves.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

分析報告

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Optical rotation α 25/D (c=1 in DMF): -21.0 - -18.0 °
Solubility (1 mmole in 2 ml DMF): clearly soluble

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable