8.52345

Fmoc-Gla(OtBu)2-OH

Novabiochem^®

• 同義詞: Fmoc-Gla(OtBu)2-OH, Fmoc-γ-carboxy-Glu(OtBu) ₂-OH
• 經驗公式（希爾表示法）: C₂₉H₃₅NO₈
• CAS號碼: 111662-64-7
• 分子量：: 525.59
• 分類程式碼代碼: 12352209
• NACRES: NA.22

屬性

• 品質等級: 200
• 產品線: Novabiochem^®
• 形狀: solid
• 反應適用性: reaction type: Fmoc solid-phase peptide synthesis
• 製造商／商標名: Novabiochem^®
• 應用: peptide synthesis
• 官能基: carboxylic acid
• 儲存溫度: 2-8°C
• InChI: 1S/C29H35NO8/c1-28(2,3)37-25(33)21(26(34)38-29(4,5)6)15-23(24(31)32)30-27(35)36-16-22-19-13-9-7-11-17(19)18-12-8-10-14-20(18)22/h7-14,21-23H,15-16H2,1-6H3,(H,30,35)(H,31,32)/t23-/m0/s1
• InChI 密鑰: XJRUHYXXHXECDI-QHCPKHFHSA-N

描述

一般說明

Fmoc-Gla(OtBu)2-OH is a building block for the introduction of γ-carboxyglutamic acid (Gla). γ -Carboxylation of glutamic acid is a rare post-translational modification that occurs in blood coagulation factors and in some snake and cone snail venoms ^[1].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

^[1] P. K. Bandyopadhyay (2002) Proc. Natl. Acad. Sci. USA, 99, 1264 .

分析報告

Colour (visual): white to slight yellow to slight red
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.
European Union for cosmetic colour additives.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable