8.51061

2-Chlorotrityl chloride

Novabiochem^®

• 同義詞: 2-Chlorotrityl chloride
• 經驗公式（希爾表示法）: C₁₉H₁₄Cl₂
• CAS號碼: 42074-68-0
• 分子量：: 313.22
• MDL號碼: MFCD00040399
• 分類程式碼代碼: 12352107
• 酶委員會索引編號: 255-647-3
• NACRES: NA.22

屬性

• 品質等級: 200
• 產品線: Novabiochem^®
• 化驗: ≥95.0% (HPLC)
• 形狀: powder
• 製造商／商標名: Novabiochem^®
• mp: 133.0-137.0 °C
• 應用: peptide synthesis
• 儲存溫度: 2-30°C
• SMILES 字串: ClC(c3c(cccc3)Cl)(c2ccccc2)c1ccccc1
• InChI: 1S/C19H14Cl2/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H
• InChI 密鑰: JFLSOKIMYBSASW-UHFFFAOYSA-N

描述

一般說明

Hyperacid-labile ester protecting group ^[1]. Introduced under extremely mild conditions by reacting together the acid, trityl chloride and DIPEA in DCM. Ideal for the protection of the C-terminal carboxylic acid group of C-terminal protected peptide fragments, monoprotection of diacids and as a general carboxylic acid protecting group in organic synthesis.


Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Literature references

^[1] P. Athanassopoulos, et al. (1995) Tetrahedron Lett., 36, 5645.

聯結

Replaces: 01-63-0045

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Melting range (lower value): ≥ 133 °C
Melting range (upper value): ≤ 137 °C
Assay (HPLC, area%): ≥ 95.0 % (a/a)

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS05,GHS07
• 訊號詞: Warning
• 危險聲明: H290 - H315 - H319 - H335
• 防範說明: P234 - P261 - P264 - P271 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 8A - Combustible, corrosive hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable