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Key Documents

8.51028

Sigma-Aldrich

Bis-Boc-amino-oxyacetic acid

Novabiochem®

同義詞:

Bis-Boc-amino-oxyacetic acid, Boc 2-Aoa-OH

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About This Item

經驗公式(希爾表示法):
C12H21NO7 · xH2O
分子量::
291.30 (anhydrous basis)
分類程式碼代碼:
12352209
NACRES:
NA.22

品質等級

產品線

Novabiochem®

化驗

≥97% (TLC)

形狀

powder

反應適用性

reagent type: ligand

製造商/商標名

Novabiochem®

應用

peptide synthesis

儲存溫度

2-8°C

一般說明

This reagent can be used to introduce a hydroxylamine functionality to N-terminal or side-chain amino groups. Hydroxylamine-labeled peptides prepared in this manner can be ligated in aqueous solution at pH 3.5 to aldehyde-containing peptides via oxime formation. This bis-protected derivative eliminates oligomer formation which can occur with mono-protected hydroxylamine reagents as a result of double acylation. Coupling of this derivative should be done using an OSu ester.

Literature references

[1] J. C. Spetzler & T. Hoeg-Jensen (2001) J. Peptide Sci., 7, 537.

聯結

Replaces: 01-63-0129

分析報告

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 97 %
Water (K. F.): 3.0 - 8.0 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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