8.20925

2-Octanol

for synthesis

• 同義詞: 2-Octanol, Hexyl methyl carbinol, 2-Capryl alcohol
• 線性公式: CH₃(CH₂)₅CH(OH)CH₃
• CAS號碼: 123-96-6
• 分子量：: 130.23
• MDL號碼: MFCD00004591
• 分類程式碼代碼: 12352104
• 酶委員會索引編號: 204-667-0
• NACRES: NA.22

屬性

• 蒸汽壓力: 0.25 hPa ( 20 °C)
• 品質等級: 200
• 化驗: ≥98% (GC)
• 形狀: oil
• 自燃溫度: 255-260 °C
• 效力: 6100 mg/kg LD₅₀, oral (Rat)
• expl. lim.: 0.80-7.40 % (v/v)
• bp: 177-182 °C/1013 hPa
• mp: -38 °C
• 轉變溫度: flash point 71 °C
• 密度: 0.82 g/cm³ at 20 °C
• 儲存溫度: 2-30°C
• InChI: 1S/C8H18O/c1-3-4-5-6-7-8(2)9/h8-9H,3-7H2,1-2H3
• InChI 密鑰: SJWFXCIHNDVPSH-UHFFFAOYSA-N

描述

應用

• Development of a mixed solvent system for the efficient resolution of (R, S)-2-octanol catalyzed by magnetite-immobilized lipase: This study presents a novel solvent system enhancing the enantioselectivity and activity of lipase in the resolution of 2-octanol, a key intermediate in synthesizing chiral building blocks used in drug development (Liu et al., 2014).
• Efficient Kinetic Resolution of (R,S)-2-Octanol Catalyzed by Magnetite-Immobilized Yarrowia lipolytica Lipase in Mixed Ionic Liquids: This research explores using ionic liquids with immobilized lipase for resolving 2-Octanol, crucial for producing enantiopure substances in pharmacological synthesis (Liu et al., 2014).
• Effect of hydrazyl radical on the selectivity of γ-alumina with different sizes of pores for dehydration of 2-octanol through radical elimination mechanism: Investigates the interaction between hydrazyl radicals and 2-octanol on γ-alumina, relevant for understanding catalytic mechanisms in material science (Alidoust et al., 2023).
• Process hazard evaluation for catalytic oxidation of 2-octanol with hydrogen peroxide using calorimetry techniques: Assesses the safety and kinetic parameters of 2-octanol oxidation, important for chemical process design in industrial and academic settings (Sun et al., 2019).
• Enhancing the resolution of (R, S)-2-octanol catalyzed by magnetic cross-linked lipase aggregates using an alternating magnetic field: Describes a method to improve the enantioselective resolution of 2-Octanol using magnetic fields, potentially useful for scaling up chiral resolutions in pharmaceutical manufacturing (Liu et al., 2015).

分析報告

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.820 - 0.822
Identity (IR): passes test

安全資訊

• 象形圖: GHS05
• 訊號詞: Danger
• 危險聲明: H318
• 防範說明: P280 - P305 + P351 + P338
• 危險分類: Eye Dam. 1
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 159.8 °F - closed cup
• 閃點（°C）: 71 °C - closed cup