8.20122

Benzamidine hydrochloride hydrate

for synthesis

• 同義詞: Benzamidine hydrochloride hydrate
• 經驗公式（希爾表示法）: C₇H₈N₂ · xHCl · yH₂O
• CAS號碼: 206752-36-5
• 分子量：: 120.15 (anhydrous free base basis)
• MDL號碼: MFCD00066285
• 分類程式碼代碼: 12352107
• 酶委員會索引編號: 216-795-4
• NACRES: NA.22

屬性

• 品質等級: 200
• 化驗: ≥98.5% (HPLC)
• 形狀: powder
• pH值: 5 (20 °C, 50 g/L in H₂O)
• mp: 80-84 °C
• 儲存溫度: 2-30°C
• InChI: 1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)/p+1
• InChI 密鑰: PXXJHWLDUBFPOL-UHFFFAOYSA-O

描述

應用

• Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes.: This study investigates the interaction of benzamidine hydrochloride hydrate as a serine protease inhibitor, focusing on its binding mechanism in the presence of water molecules. Utilizing neutron crystallography, the research provides insights into the dynamic role of water in enhancing the binding affinity and stability of the inhibitor to trypsin. This understanding is crucial for the design of more effective protease inhibitors in pharmaceutical applications (Schiebel et al., 2018).

分析報告

Assay (HPLC, area%): ≥ 98.5 % (a/a)
Water (K. F.): 7.0 - 13.0 %
Identity (IR): passes test

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable