8.18043

Trifluoromethanesulfonic anhydride

for synthesis

• 同義詞: Trifluoromethanesulfonic anhydride
• 線性公式: (CF₃SO₂)₂O
• CAS號碼: 358-23-6
• 分子量：: 282.14
• MDL號碼: MFCD00000408
• 分類程式碼代碼: 12352106
• 酶委員會索引編號: 206-616-8
• NACRES: NA.22

屬性

• 品質等級: 200
• 化驗: ≥99.0% (acidimetric)
• 形狀: liquid
• 效力: 1012 mg/kg LD₅₀, oral (Rat)
• 密度: 1.71 g/cm³ at 20 °C
• 儲存溫度: 2-30°C
• InChI: 1S/C2F6O5S2/c3-1(4,5)14(9,10)13-15(11,12)2(6,7)8
• InChI 密鑰: WJKHJLXJJJATHN-UHFFFAOYSA-N

描述

應用

• Electrophilic activation using trifluoromethanesulfonic anhydride: This method is utilized for transformations of amides, sulfoxides, and phosphorus oxides through nucleophilic trapping, highlighting its versatility in organic synthesis (Huang and Kang, 2022).
• Triflic anhydride in organic synthesis: A comprehensive review of triflic anhydride′s roles, focusing on its application across various organic transformations (Qin, Cheng, and Jiao, 2023).
• Synthesis of nitriles: Employing trifluoromethanesulfonic anhydride for converting aldoximes to nitriles under mild conditions, showcasing an innovative application in nitrile synthesis (Uludag, 2020).
• Hydrotrifluoromethylthiolation of alkenes: Uses trifluoromethanesulfonic anhydride for the hydrotrifluoromethylthiolation of unactivated alkenes and alkynes, expanding the utility of this reagent in radical reactions (Ouyang, Xu, and Qing, 2019).
• Low-cost trifluoromethylation reagent: Discusses the economic benefits and wide-ranging applications of trifluoromethanesulfonic anhydride in trifluoromethylation processes (Ouyang, Xu, and Qing, 2018).

分析報告

Assay (acidimetric): ≥ 99.0 %
Density (d 20 °C/ 4 °C): 1.715 - 1.720
Identity (IR): passes test

安全資訊

• 象形圖: GHS03,GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H272 - H302 - H314 - H335
• 防範說明: P210 - P220 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1 - Ox. Liq. 2 - Skin Corr. 1B - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 5.1B - Oxidizing hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: not determined
• 閃點（°C）: not determined